Number of Metabolic Syndrome Risk Factors is Related to Carotid Intima-Media Thickness in Rheumatoid Arthritis Patients

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dc.contributor.authorGokmen, Ferhat
dc.contributor.authorTemiz, Ahmet
dc.contributor.authorAkbal, Ayla
dc.contributor.authorSen, Hacer
dc.contributor.authorZateri, Coskun
dc.contributor.authorGokmen, Esra
dc.contributor.authorBozkurt, Emre
dc.date.accessioned2025-01-27T20:20:08Z
dc.date.available2025-01-27T20:20:08Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjectives: This study aims to investigate the relationship between carotid intima-media thickness (CIMT) and clinical and metabolic variables in rheumatoid arthritis (RA) patients. Patients and methods: The study included 76 RA patients (18 males, 58 females; mean age 50.1+/-9.8 years; range 21 to 69 years) and 42 control subjects (11 males, 31 females; mean age 49.2+/-9.7; range 28 to 66 years). Erythrocyte sedimentation rate, C-reactive protein, and disease activity score were used to assess disease activation. Rheumatoid factor, anti-cyclic citrullinated peptide antibodies, and metabolic syndrome components (fasting blood glucose, high density lipoprotein-cholesterol, triglyceride, blood pressure, and waist circumference) were measured. Results: Mean disease duration was 6.9+/-6.5 years. Patients with RA had higher CIMT than the controls (0.8+/-0.1 and 0.6+/-0.2, respectively; p< 0.001). Statistically significant positive correlations were observed between CIMT and age, erythrocyte sedimentation rate, C-reactive protein, and systolic and diastolic blood pressure. The CIMT in RA patients having metabolic syndrome risk components ranging from one to four were 0.76+/-0.16, 0.82+/-0.14, 0.86+/-0.13, and 0.92+/-0.13, respectively. CIMT was positively correlated with the number of metabolic syndrome risk components. Conclusion: Our study has shown elevated CIMT in RA. Presence of metabolic syndrome components in RA patients increases tendency to atherosclerosis and constitutes a severe risk for cardiovascular disease.
dc.identifier.doi10.5606/ArchRheumatol.2015.5109
dc.identifier.endpage129
dc.identifier.issn1309-0291
dc.identifier.issn2148-5046
dc.identifier.issue2
dc.identifier.scopus2-s2.0-84930324269
dc.identifier.scopusqualityN/A
dc.identifier.startpage124
dc.identifier.trdizinid173978
dc.identifier.urihttps://doi.org/10.5606/ArchRheumatol.2015.5109
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/173978
dc.identifier.urihttps://hdl.handle.net/20.500.12428/21580
dc.identifier.volume30
dc.identifier.wosWOS:000357192400006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherTurkish League Against Rheumatism
dc.relation.ispartofArchives of Rheumatology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectCardiovascular risk
dc.subjectcarotid intima media thickness
dc.subjectmetabolic syndrome risk factors
dc.subjectrheumatoid arthritis
dc.titleNumber of Metabolic Syndrome Risk Factors is Related to Carotid Intima-Media Thickness in Rheumatoid Arthritis Patients
dc.typeArticle

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