Which is More Important and Insidious in Dialysis Patients? Occult Hepatitis B or Occult Hepatitis C?

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dc.authoridSener, Alper/0000-0003-2774-8601
dc.contributor.authorGazel, Ozlem Zanapalioglu
dc.contributor.authorSener, Alper
dc.date.accessioned2025-01-27T21:04:19Z
dc.date.available2025-01-27T21:04:19Z
dc.date.issued2020
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjectives: The aim of this study was to investigate the presence of occult hepatitis B infection (OBI) and Occult hepatitis C infection (OCI) in hemodialysis patients and to determine whether there is an activation in the follow-up or not. Materials and Methods: Demographic data, causes of renal failure, access to hemodialysis, duration of hemodialysis, alanine aminotransferase (ALT) levels, hepatitis indicators of 100 HD patients with normal ALT levels were recorded in this study. Serum anti-hepatitis B core antibody (anti-HBc) immunoglobulin G (IgG) was tested with ELISA (Architecht, Abbott). Serum hepatitis B virus (HBV)-DNA, HCV-RNA [in peripheral blood mononuclear cells (PBMNC)] were studied with real-time polymerase chain reaction method. Results: Anti-HBc IgG positivity was detected in 27% of patients, but with no isolated anti-HBc IgG positivity. In 4% of the patients, HBV-DNA positivity and OBI infection were detected. None of the patients showed HCV-RNA positivity in serum and in PBMNC, therefore OCI was not detected. None of the patients developed OBI or OCI activation in five-years follow-up. Renal transplantation was performed in one of the OBI patients and lifelong prophylaxis was planned with oral antiviral medication. Conclusion: Presence of OCI is lower than OBI in hemodialysis patients.
dc.identifier.doi10.4274/vhd.galenos.2019.2019.0032
dc.identifier.endpage42
dc.identifier.issn1307-9441
dc.identifier.issn2147-2939
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85208515618
dc.identifier.scopusqualityN/A
dc.identifier.startpage39
dc.identifier.trdizinid377843
dc.identifier.urihttps://doi.org/10.4274/vhd.galenos.2019.2019.0032
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/377843
dc.identifier.urihttps://hdl.handle.net/20.500.12428/27609
dc.identifier.volume26
dc.identifier.wosWOS:000530141100008
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherGalenos Yayincilik
dc.relation.ispartofViral Hepatit Dergisi-Viral Hepatitis Journal
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectOccult Hepatitis B
dc.subjectoccult hepatitis C
dc.subjecthemodialysis
dc.titleWhich is More Important and Insidious in Dialysis Patients? Occult Hepatitis B or Occult Hepatitis C?
dc.typeArticle

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