Advances in Apolipoprotein-A4 Biosensing Assays for Depression Diagnosis

dc.authoridKarav, Sercan / 0000-0003-4056-1673
dc.contributor.authorBahaabadi, Zahra Jamalizadeh
dc.contributor.authorKarav, Sercan
dc.contributor.authorSahebkar, Amirhossein
dc.date.accessioned2025-05-29T02:57:44Z
dc.date.available2025-05-29T02:57:44Z
dc.date.issued2025
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractApolipoprotein-A4 (Apo-A4) is a plasma protein that plays a role in various physiological and behavioral-emotional reactions when faced with stress. Studies have shown a close relationship between Apo-A4 and the onset of depression and its symptoms. However, there is currently no reliable laboratory approach to confirm the diagnosis of depression. Therefore, the development of a precise and effective technique to assess Apo-A4 might help in the early detection and screening of depression and other related psychiatric diseases, as well as in tracking and managing the course of treatment. As technology advances, biosensors have become quick, accurate, and sensitive tools for personal care and illness diagnosis. Biosensors for measuring and detecting Apo-A4 levels have recently been designed. These studies emphasized the development of accurate and sensitive diagnostic and measurement techniques. This review attempts to give a general overview of the role of Apo-A4 in depression and introduce established biosensors for its detection and measurement.
dc.identifier.doi10.1080/10408347.2025.2496503
dc.identifier.issn1040-8347
dc.identifier.issn1547-6510
dc.identifier.pmid40298379
dc.identifier.scopus2-s2.0-105003875494
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1080/10408347.2025.2496503
dc.identifier.urihttps://hdl.handle.net/20.500.12428/30162
dc.identifier.wosWOS:001478576500001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Inc
dc.relation.ispartofCritical Reviews In Analytical Chemistry
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250529
dc.subjectApo-A4
dc.subjectApolipoprotein-A4
dc.subjectbiosensor
dc.subjectdepression
dc.titleAdvances in Apolipoprotein-A4 Biosensing Assays for Depression Diagnosis
dc.typeReview

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