THE UTILITY OF HEMATOLOGICAL INDICES AT THE INITIAL ADMISSION TO THE NEUROSURGERY CLINIC IN CERVICAL DISC HERNIATION

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dc.contributor.authorCinpolat, Havva Yasemin
dc.contributor.authorAkar, Ali
dc.contributor.authorMalcok, Umit Ali
dc.contributor.authorAlkan, Sevil
dc.date.accessioned2025-01-27T20:39:18Z
dc.date.available2025-01-27T20:39:18Z
dc.date.issued2024
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: This study aimed to investigate hematological indices to predict spontaneous regression in patients with cervical disc herniation (CDH) during the initial visit to outpatient clinics. Materials and Methods: This retrospective study was carried out at a single center by reviewing laboratory parameters to assess the outcomes of CDH patients. The cohort consisted of patients with CDH who had undergone surgery, those who had undergone conservative treatment and achieved spontaneous regression, and a control group without CDH. The laboratory data consisted of the neutrophil-tolymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), and systemic immune-inflammatory index (SIII). Results: Differences in the NLR, MLR, and SIII were statistically significant across groups (p<0.001). Compared with the spontaneous regression and control groups, the surgical intervention group presented significantly greater NLR, MLR, and SIII values. According to the comparison of the patients with CDH in terms of the level of herniation, there were no significant differences at the C4-C5 and upper levels, whereas there was a statistically significant increase in the NLR, MLR, and SIII in the surgical intervention group compared with the spontaneous regression group at the C6-C7 level (p = 0.015, p<0.001, and p = 0.003, respectively). Conclusion: This study provides valuable insights into the use of hematological indices to predict the need for surgical intervention in CDH patients. The observed associations emphasize their practical use, providing a way for further research and their inclusion in routine diagnostic protocols for CDH management.
dc.identifier.doi10.69601/meandrosmdj.1559114
dc.identifier.endpage435
dc.identifier.issn2149-9063
dc.identifier.issue4
dc.identifier.startpage424
dc.identifier.urihttps://doi.org/10.69601/meandrosmdj.1559114
dc.identifier.urihttps://hdl.handle.net/20.500.12428/23917
dc.identifier.volume25
dc.identifier.wosWOS:001385863800005
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherGalenos Publ House
dc.relation.ispartofMeandros Medical and Dental Journal
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectcervical disc herniation
dc.subjectinflammation
dc.subjectsystemic immune-inflammatory index
dc.subjectneutrophil-to-lymphocyte ratio
dc.subjectmonocyte-to-lymphocyte ratio
dc.titleTHE UTILITY OF HEMATOLOGICAL INDICES AT THE INITIAL ADMISSION TO THE NEUROSURGERY CLINIC IN CERVICAL DISC HERNIATION
dc.typeArticle

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