Fragmented QRS is associated with frequency of premature ventricular contractions in patients without overt cardiac disease

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dc.contributor.authorTemiz, Ahmet
dc.contributor.authorGazi, Emine
dc.contributor.authorAltun, Burak
dc.contributor.authorGungor, Omer
dc.contributor.authorBarutcu, Ahmet
dc.contributor.authorBekler, Adem
dc.contributor.authorTan, Yusuf Ziya
dc.date.accessioned2025-01-27T20:53:49Z
dc.date.available2025-01-27T20:53:49Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: In this study, we aimed to demonstrate whether the presence of fragmented QRS (fQRS) is associated with the frequency of premature ventricular contractions (PVCs). Methods: We retrospectively analyzed 282 cases by 24-hour Holter monitorings (HMs) between August 2012 and February 2013. Firstly, the patients were divided into 2 groups with respect to presence of fQRS and then divided into 3 groups with respect to frequency of PVCs as Group 1: seldom PVC (<120 PVCs/day), Group 2: moderate-frequency PVC (120-720 PVCs/day), and Group 3: frequent PVC (>720 PVCs/day). We investigated the predictors of frequent PVCs by using multinomial logistic regression analysis. Results: Ninety-eight patients had fQRS. There was no difference between the 2 groups with respect to body mass index, gender, hypertension, and diabetes mellitus. Patients with fQRS were older (54.9 +/- 15.6 vs. 47.0 +/- 16.3, p<0.001) and had more family history of coronary artery disease (25% vs. 13%, p=0.012). Patients with fQRS was more likely to be on aspirin therapy (28.6% vs. 10.4%, p<0.001) and have a larger left atrium diameter (33.5 +/- 5.7 vs. 30.4 +/- 5.8, p=0.001). Presence of fQRS was significantly associated with the frequency of PVCs (for frequent PVC 27.7% vs. 7.6%, p<0.001; for moderate-frequency PVC 18.4% vs. 11.4%, p=0.012); 26.2% of Group 1 (n=202) had fQRS, 46.2% of Group 2 (n=39) had fQRS, and 65.9% of Group 3 (n=41) had fQRS. In the multinomial regression analysis, only age (odds ratio: 4.24, 95% confidence interval 2.08-8.64, p=0.001) and fQRS (odds ratio: 2.11, 95% confidence interval 1.00-4.45, p=0.05) were predictors of frequent PVCs. Conclusion: This study demonstrated that the presence of fQRS is associated with frequent PVCs in patients without overt structural heart disease.
dc.identifier.doi10.5152/akd.2014.5467
dc.identifier.endpage462
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.issue6
dc.identifier.pmid25430411
dc.identifier.scopus2-s2.0-84979092797
dc.identifier.scopusqualityN/A
dc.identifier.startpage456
dc.identifier.trdizinid248940
dc.identifier.urihttps://doi.org/10.5152/akd.2014.5467
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/248940
dc.identifier.urihttps://hdl.handle.net/20.500.12428/25853
dc.identifier.volume15
dc.identifier.wosWOS:000357329700003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTurkish Soc Cardiology
dc.relation.ispartofAnatolian Journal of Cardiology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectfragmented QRS
dc.subjectpremature ventricular contraction
dc.subjectHolter monitoring
dc.titleFragmented QRS is associated with frequency of premature ventricular contractions in patients without overt cardiac disease
dc.typeArticle

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