Revealing the Potency of Growth Factors in Bovine Colostrum

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dc.authoridde Brito Alves, Jose Luiz/0000-0003-4696-3809
dc.authoridKoch, Wojciech/0000-0001-8749-9657
dc.authoridKARAV, SERCAN/0000-0003-4056-1673
dc.authoridLombardo, Mauro/0000-0001-7509-5487
dc.authoridRaposo, Antonio/0000-0002-5286-2249
dc.authoridYalcintas, Mert/0009-0008-0447-1076
dc.authoridBordiga, Matteo/0000-0001-6587-9843
dc.contributor.authorYalcintas, Yalcin Mert
dc.contributor.authorDuman, Hatice
dc.contributor.authorLopez, Jose M. Miranda
dc.contributor.authorPortocarrero, Alicia C. Mondragon
dc.contributor.authorLombardo, Mauro
dc.contributor.authorKhallouki, Farid
dc.contributor.authorKoch, Wojciech
dc.date.accessioned2025-01-27T21:01:47Z
dc.date.available2025-01-27T21:01:47Z
dc.date.issued2024
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractColostrum is a nutritious milk synthesized by mammals during the postpartum period, and its rich bioactive components has led to a global increase in the consumption of bovine colostrum as a supplement. Bovine colostrum contains key components such as immunoglobulins, oligosaccharides, lactoferrin and lysozyme. It is a special supplement source due to its natural, high bioavailability and high concentrations of growth factors. Growth factors are critical to many physiological functions, and considering its presence in the colostrum, further research must be conducted on its safe application in many bodily disorders. Growth factors contribute to wound healing, muscle and bone development, and supporting growth in children. Additionally, the molecular mechanisms have been explored, highlighting the growth factors roles in cell proliferation, tissue regeneration, and the regulation of immune responses. These findings are crucial for understanding the potential health effects of bovine colostrum, ensuring its safe use, and forming a basis for future clinical applications. This review article examines the growth factors concentration in bovine colostrum, their benefits, clinical studies, and molecular mechanisms.
dc.identifier.doi10.3390/nu16142359
dc.identifier.issn2072-6643
dc.identifier.issue14
dc.identifier.pmid39064802
dc.identifier.scopus2-s2.0-85199633355
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.3390/nu16142359
dc.identifier.urihttps://hdl.handle.net/20.500.12428/27186
dc.identifier.volume16
dc.identifier.wosWOS:001277208500001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMdpi
dc.relation.ispartofNutrients
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectcolostrum
dc.subjectgrowth factors
dc.subjectimmune responses
dc.subjecthealth benefits
dc.subjectnutritional supplements
dc.titleRevealing the Potency of Growth Factors in Bovine Colostrum
dc.typeReview Article

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