Is Single Measurement Enough to Get a Reliable Result with Optical Coherence Tomography?

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dc.authoridKomur, Baris/0000-0002-9347-0209
dc.contributor.authorComez, Arzu Taskiran
dc.contributor.authorEser, Ilker
dc.contributor.authorBakar, Coskun
dc.contributor.authorKomur, Baris
dc.date.accessioned2025-01-27T20:47:24Z
dc.date.available2025-01-27T20:47:24Z
dc.date.issued2012
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractPurpose: To evaluate the repeatability and reliability of retinal nerve fiber layer (RNFL) thickness measurements using optical coherence tomography (OCT). Material and Method: Two hundred sixty-six eyes of 135 subjects (glaucoma, glaucoma suspects and healthy) were included in this study. Three sequential inferior, superior, nasal and temporal RNFL thickness measurements were performed using Spectral OCT [Opko/OTI, Inc., Miami, FL] by one operator at one session without pupillary dilatation. The differences between these three measurements of each quadrant in each eye were compared in microns and percentages. Repeated measures analysis of variance was performed for statistical analysis. Reliability is measured by intraclass correlation coefficient (ICC) for each quadrant. Results: ICCs of all quadrants ranged between 0.77 and 0.92, with the measurements of nasal quadrant being the least reproducible and the inferior being the most reproducible of all quadrants. RNFL measurement errors over 20% were seen in 9.63% of nasal quadrant, 5.3% of temporal quadrant, 0.6% of superior quadrant and only 0.3% of inferior quadrant measurements. Discussion: In order to get more repeatable and reliable results with OCT, sequential measurements more than one should be considered. We believe that special attention is required in the analysis of data of nasal and temporal quadrants.
dc.identifier.doi10.4274/tjo.42.680770
dc.identifier.endpage15
dc.identifier.issn1300-0659
dc.identifier.issn2147-2661
dc.identifier.issue1
dc.identifier.scopus2-s2.0-84859361238
dc.identifier.scopusqualityN/A
dc.identifier.startpage11
dc.identifier.trdizinid141280
dc.identifier.urihttps://doi.org/10.4274/tjo.42.680770
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/141280
dc.identifier.urihttps://hdl.handle.net/20.500.12428/24884
dc.identifier.volume42
dc.identifier.wosWOS:000219202300003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherTurkish Ophthalmological Soc
dc.relation.ispartofTurk Oftalmoloji Dergisi-Turkish Journal of Ophthalmology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectGlaucoma
dc.subjectoptical coherence tomography
dc.subjectreliability
dc.subjectrepeatability
dc.subjectretinal nerve fiber layer
dc.titleIs Single Measurement Enough to Get a Reliable Result with Optical Coherence Tomography?
dc.title.alternativeOptik Koherens Tomografi ile Güvenilir Sonuç Almak için Tek Ölçüm Yeterli mi?
dc.typeArticle

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