Effects of Waterborne Lead Exposure in Mozambique Tilapia: Oxidative Stress, Osmoregulatory Responses, and Tissue Accumulation

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dc.contributor.authorKaya, Hasan
dc.contributor.authorAkbulut, Mehmet
dc.date.accessioned2025-01-27T21:03:46Z
dc.date.available2025-01-27T21:03:46Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractWe studied the oxidative stress and osmoregulatory damage as well as the accumulation of lead in Mozambique Tilapia Oreochromis mossambicus exposed to different sublethal concentrations-low, medium, and high (0.5, 2.5, and 5.0 mg/L)-of waterborne lead for 14 d in a semistatic condition. The accumulated levels of Na+, K+-ATPase, glutathione (GSH), and thiobarbituric acid reactive substances (TBARS) were determined from samples of gill, liver, intestine, brain, kidney, and muscle tissues. At the end of the experiment, the GSH levels of most tissues were higher in the treated group than in the control group (especially in the liver and kidney) but lower in the intestine. The levels of TBARS in the gill and brain tissues of the fish exposed to high lead doses were significantly higher than those of fish in the control group. Na+, K+-ATPase activity seemed to be significantly inhibited in the gill, intestine, and brain tissues across all treatment groups. At the end of the study, the total amount of lead that had accumulated within the various tissues ranked as follows: intestines > kidney > brain > gill > liver > muscle. Our findings suggest that sublethal concentrations of lead can disrupt the health of Mozambique Tilapia and cause oxidative stress and osmoregulatory damage.
dc.description.sponsorshipCanakkale Onsekiz Mart University Scientific Foundation [2010/26]
dc.description.sponsorshipThis study was supported by the Canakkale Onsekiz Mart University Scientific Foundation (project 2010/26).
dc.identifier.doi10.1080/08997659.2014.1001533
dc.identifier.endpage87
dc.identifier.issn0899-7659
dc.identifier.issn1548-8667
dc.identifier.issue2
dc.identifier.pmid25951052
dc.identifier.scopus2-s2.0-84935898367
dc.identifier.scopusqualityQ3
dc.identifier.startpage77
dc.identifier.urihttps://doi.org/10.1080/08997659.2014.1001533
dc.identifier.urihttps://hdl.handle.net/20.500.12428/27439
dc.identifier.volume27
dc.identifier.wosWOS:000356381800002
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofJournal of Aquatic Animal Health
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectTrout Salmo-Gairdneri
dc.subjectRainbow-Trout
dc.subjectAnguilla-Anguilla
dc.subjectChronic Toxicity
dc.subjectCopper Exposure
dc.subjectK-Atpase
dc.subjectCadmium
dc.subjectLiver
dc.subjectGill
dc.subjectMetallothionein
dc.titleEffects of Waterborne Lead Exposure in Mozambique Tilapia: Oxidative Stress, Osmoregulatory Responses, and Tissue Accumulation
dc.typeArticle

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