Effects of dietary marine sulphated polysaccharides (Algimun®) on growth performance, immune responses and disease resistance of juvenile gilthead seabream (Sparus aurata) to Photobacterium damselae subsp. piscicida

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dc.authoridGuroy, Betul/0000-0002-4298-6256
dc.authoridGuroy, Derya/0000-0002-8254-1403
dc.contributor.authorGuroy, Derya
dc.contributor.authorGuroy, Betul
dc.contributor.authorBilen, Soner
dc.contributor.authorTerzi, Ertugrul
dc.contributor.authorKenanoglu, Osman Nezih
dc.contributor.authorGarcia-Suarez, Maria
dc.contributor.authorMarzin, Daniele
dc.date.accessioned2025-01-27T21:03:44Z
dc.date.available2025-01-27T21:03:44Z
dc.date.issued2022
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractThe present study evaluated the effects of a dietary mix of marine sulphated polysaccharides, named Algimun (R) (AL), supplementation to gilthead seabream (Sparus aurata) juveniles in terms of growth performance, immune responses, and resistance against Photobacterium damselae subsp. piscicida. A total of 240 fish (initial mean weight of 6.00 +/- 0.03 g) was randomly separated into 12 tanks (400 L, 20 fish per tank) distributed in four replicates. Fish were fed three experimental diets: a basal diet (Control), and a basal diet with two inclusion rates of Algimun (R) as 3 g/kg (AL0.3) and 5 g/kg (AL0.5) for 30 days before bacterial infection with P. damselae subsp. piscicida. After a 30-day feeding-period, growth performance was significantly improved in AL0.3 and AL0.5 groups compared to the control group (P < 0.05). AL0.3 and AL0.5 groups showed significantly higher lysozyme activity and myelopemxidase activity when compared to the control group (P < 0.05). The gene expression of immune mediators (IL-1 beta, IL-6, IL-10, IL-18, TNF-alpha and COX-2) was significantly upregulated in the intestine, spleen and head kidney in AL0.3 and AL0.5 groups when compared to the control group (P < 0.05). Eight days post-challenge, the survival rate against P. damselae subsp. piscicida was numerically higher in fish within AL0.3 and AL0.5 groups compared to control (+20%). The study findings suggest that marine sulphated polysaccharides (Algimun (R)) could be used as an immunomodulator in gilthead seabream to support animal's health and boost resistance in case of disease outbreak.
dc.identifier.doi10.1016/j.fsi.2022.07.054
dc.identifier.endpage1147
dc.identifier.issn1050-4648
dc.identifier.issn1095-9947
dc.identifier.pmid35870744
dc.identifier.scopus2-s2.0-85135725600
dc.identifier.scopusqualityQ1
dc.identifier.startpage1139
dc.identifier.urihttps://doi.org/10.1016/j.fsi.2022.07.054
dc.identifier.urihttps://hdl.handle.net/20.500.12428/27429
dc.identifier.volume127
dc.identifier.wosWOS:000878589500006
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAcademic Press Ltd- Elsevier Science Ltd
dc.relation.ispartofFish & Shellfish Immunology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectMarine fish
dc.subjectSeaweed
dc.subjectMarine sulphate polysaccharide
dc.subjectNutrition
dc.subjectImmunomodulation
dc.titleEffects of dietary marine sulphated polysaccharides (Algimun®) on growth performance, immune responses and disease resistance of juvenile gilthead seabream (Sparus aurata) to Photobacterium damselae subsp. piscicida
dc.typeArticle

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