The Great Harmony in Translational Medicine: Biomaterials and Stem Cells

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dc.authoridARSLAN, Yavuz Emre/0000-0003-3445-1814
dc.contributor.authorErten, Evren
dc.contributor.authorArslan, Yavuz Emre
dc.coverage.doi10.1007/978-3-030-10486-3
dc.date.accessioned2025-01-27T20:46:15Z
dc.date.available2025-01-27T20:46:15Z
dc.date.issued2018
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractThanks to novel approaches and emerging technologies, tissue engineering and regenerative medicine have made a great effort to regenerate damaged tissue or organ with no donor needed. The approaches involve two fundamental components: bioengineered scaffolds and stem cells. Bioengineered scaffolds which can also be enriched with bioactive molecules such as cytokines, growth factors, and so on have been fabricated using a wide range of synthetically or naturally derived biodegradable and biocompatible polymers. These scaffolds should support cell attachment, migration, proliferation, and/or differentiation by mimicking the duty of native extracellular matrix. Stem cells are the other significant players in formation of the neotissue. Stem cells, bone marrow, or adipose-derived mesenchymal stem cells, in particular, have been widely used for this purpose. Recently, investigators have preferred to use progenitor cells including cardiac and neural cells in tissue engineering and regenerative medicine applications. The synergy of the bioengineered scaffolds and autologous stem cells is crucial for the successful reconstruction of damaged or missing tissues. This review summarizes a number of excellent studies conducted on current applications of bioengineered scaffolds, novel fabrication methods, stem cells used in tissue engineering and regenerative medicine, and the future of the tissue-engineered products.
dc.identifier.doi10.1007/5584_2018_231
dc.identifier.endpage39
dc.identifier.isbn978-3-030-10486-3
dc.identifier.isbn978-3-030-10485-6
dc.identifier.issn0065-2598
dc.identifier.issn2214-8019
dc.identifier.pmid29876869
dc.identifier.scopus2-s2.0-85061095400
dc.identifier.scopusqualityQ1
dc.identifier.startpage21
dc.identifier.urihttps://doi.org/10.1007/5584_2018_231
dc.identifier.urihttps://hdl.handle.net/20.500.12428/24847
dc.identifier.volume1119
dc.identifier.wosWOS:000457973100003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer International Publishing Ag
dc.relation.ispartofCell Biology and Translational Medicine, Vol 4: Stem Cells and Cell Based Strategies in Regeneration
dc.relation.publicationcategoryKitap Bölümü - Uluslararası
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectStem cells
dc.subjectBioengineered scaffolds
dc.subjectIndustry
dc.subjectTranslational medicine
dc.subjectRegenerative therapy
dc.subjectTissue engineering
dc.titleThe Great Harmony in Translational Medicine: Biomaterials and Stem Cells
dc.typeBook Chapter

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