Characterisation and biological activities of synthesised copper oxide nanoparticles from the Pimpinella anisum L. aqueous extract

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dc.authoridDemir, Neslihan/0000-0002-2347-8344
dc.contributor.authorSucu, S.
dc.contributor.authorDemir, N.
dc.date.accessioned2025-01-27T20:14:12Z
dc.date.available2025-01-27T20:14:12Z
dc.date.issued2024
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractNanoparticles can be synthesised by several methods. Due to the long duration, high cost, and toxic by-products of chemical and physical methods, the biological method has become more preferred. Among various sources such as bacteria, fungi, or yeast, the use of plants in biological synthesis has proven to be the most ideal. Many metals can be used in the biological method, including copper oxide (CuO). In this study, copper oxide nanoparticles (CuONPs) were synthesised using Pimpinella anisum L. aqueous extract. For characterisation of the CuONPs, UV-Visible Spectroscopy (UV-Vis), Scanning Electron Microscopy (SEM), Energy Dispersion Spectroscopy (EDS), and Fourier Transform Infrared Spectroscopy (FT-IR) analyses were performed. The biological activity of the P. anisum extract and CuONPs was determined using DNA cleavage (agarose gel electrophoresis), antioxidant (1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity and hydrogen peroxide scavenging activity), mutagenic (Ames/Salmonella test), and catalytic (methylene blue degradation) activities. In DNA cleavage activity test, CuONPs completely denatured DNA at high concentrations (100 and 200 mu g mL(-1)) due to their oxidative activity. The results showed that both the extract and CuONPs have antioxidant properties in DPPH and hydrogen peroxide scavenging activities. According to the mutagenicity, CuONPs did not have a mutagenic effect. In catalytic activity, CuONPs degraded methylene blue within 240 min by 99.45%.
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK) [2209-A]; Canakkale Onsekiz Mart University Science and Technology Application and Research Center (COBILTUM)
dc.description.sponsorshipThis work was supported by The Scientific and Technological Research Council of Turkey (TUBITAK) with 2209-A project.We would like to thank Canakkale Onsekiz Mart University Science and Technology Application and Research Center (COBILTUM) and Prof. Dr. Mustafa YILDIZ for characterisation of CuONPs.
dc.identifier.doi10.1556/066.2024.00046
dc.identifier.endpage385
dc.identifier.issn0139-3006
dc.identifier.issn1588-2535
dc.identifier.issue3
dc.identifier.scopus2-s2.0-85203377346
dc.identifier.scopusqualityQ3
dc.identifier.startpage373
dc.identifier.urihttps://doi.org/10.1556/066.2024.00046
dc.identifier.urihttps://hdl.handle.net/20.500.12428/20992
dc.identifier.volume53
dc.identifier.wosWOS:001306626700004
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherAkademiai Kiado Zrt
dc.relation.ispartofActa Alimentaria
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectnanoparticles
dc.subjectgreen synthesis
dc.subjectPimpinella anisum
dc.subjectcopper oxide
dc.subjectbiological activity
dc.titleCharacterisation and biological activities of synthesised copper oxide nanoparticles from the Pimpinella anisum L. aqueous extract
dc.typeArticle

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