Right ventricular function and its relationship with grade of hepatosteatosis in non-alcoholic fatty liver disease

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dc.contributor.authorBekler, Adem
dc.contributor.authorGazi, Emine
dc.contributor.authorErbag, Gokhan
dc.contributor.authorBinnetoglu, Emine
dc.contributor.authorBarutcu, Ahmet
dc.contributor.authorSen, Hacer
dc.contributor.authorTemiz, Ahmet
dc.date.accessioned2025-01-27T21:00:04Z
dc.date.available2025-01-27T21:00:04Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: This study was designed to assess right ventricular systolic and diastolic function and its relationship with grade of hepatosteatosis (HS) in non-alcoholic fatty liver disease (NAFLD) patients using conventional and tissue Doppler echocardiography. Methods: NAFLD was diagnosed in 32 individuals (15 males, 17 females; 59% were grade I HS, 41% grade II-III HS) by means of ultrasonography. Twenty-two individuals, whose ultrasonography data did not show HS, comprised the control group (11 males, 11 females) and were included in the study. Right ventricular systolic and diastolic function and their relationship with grade of HS were assessed by conventional and tissue Doppler echocardiography. Additionally, right ventricular global function was assessed by myocardial performance index (MPI). Results: When compared by conventional echocardiographic parameters, there were no significant differences between the two groups. With tissue Doppler parameters, the tricuspid annulus peak early diastolic velocity and ratio of early-to-late diastolic velocity were lower in the patients than in the controls (p = 0.03, p = 0.02, respectively). The isovolumetric relaxation time and MPI were significantly higher (p < 0.001, p < 0.001, respectively) in the patient group. HS grade was positively correlated with right ventricular isovolumetric relaxation time and MPI index (r = 0.295, p = 0.03, r = 0.641, p < 0.001, respectively). Conclusion: These results show that right ventricular diastolic dysfunction (RVDD) in patients with NAFLD and degree of HS was associated with RVDD.
dc.identifier.doi10.5830/CVJA-2014-068
dc.identifier.endpage113
dc.identifier.issn1995-1892
dc.identifier.issn1680-0745
dc.identifier.issue3
dc.identifier.pmid26592905
dc.identifier.scopus2-s2.0-84941754047
dc.identifier.scopusqualityQ3
dc.identifier.startpage109
dc.identifier.urihttps://doi.org/10.5830/CVJA-2014-068
dc.identifier.urihttps://hdl.handle.net/20.500.12428/26928
dc.identifier.volume26
dc.identifier.wosWOS:000357657100007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherClinics Cardive Publ Pty Ltd
dc.relation.ispartofCardiovascular Journal of Africa
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectechocardiography
dc.subjecthepatosteatosis
dc.subjectright ventricular dysfunction
dc.titleRight ventricular function and its relationship with grade of hepatosteatosis in non-alcoholic fatty liver disease
dc.typeArticle

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