Is PSA Still the Best Marker in Diagnosis and Monitoring of Prostate Cancer?

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dc.authoridAkbas, Alpaslan/0000-0003-1470-5952
dc.authoridgulpinar, murat tolga/0000-0001-9420-3009
dc.contributor.authorAkbas, Alpaslan
dc.contributor.authorAbdulmajed, Mohamed Ismat
dc.contributor.authorGulpinar, Murat Tolga
dc.contributor.authorSancak, Eyup Burak
dc.date.accessioned2025-01-27T20:24:57Z
dc.date.available2025-01-27T20:24:57Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractProstate cancer is the second most common cancer in males. At an early stage, prostate cancer barely causes any symptoms. The presence of symptoms upon presentation usually implies the presence of locally-advanced or metastatic disease. Therefore, early detection of prostate cancer is a necessity. Serum Prostate-Specific Antigen (PSA) test and Digital Rectal Examination (DRE) are used for early detection by the urologist. However serum PSA level is not only affected by the tumours but also other factors. The limitations of serum PSA test led to the introduction and application of various PSA derivatives to improve test sensitivity and specificity. In this review article, we provide a literature review and analysis of the currently available PSA test and its derivatives compared to new and developing potential tumour markers for detection and monitoring of prostate cancer.
dc.identifier.endpage192
dc.identifier.issn1304-3889
dc.identifier.issn1304-3897
dc.identifier.issue2
dc.identifier.scopus2-s2.0-84937141506
dc.identifier.scopusqualityN/A
dc.identifier.startpage187
dc.identifier.urihttps://hdl.handle.net/20.500.12428/22395
dc.identifier.volume12
dc.identifier.wosWOS:000367541400020
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherModestum Ltd
dc.relation.ispartofEuropean Journal of General Medicine
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectPSA derivates
dc.subjectprostate cancer
dc.subjecttumour marker
dc.titleIs PSA Still the Best Marker in Diagnosis and Monitoring of Prostate Cancer?
dc.title.alternativeProstat kanseri tanısı ve görüntülemesinde PSA hala en iyi belirteç midir?
dc.typeReview Article

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