Environmentally-friendly preparation of chitosan microspheres and encapsulation studies of cinnamaldehyde: ?owards convenient sustained release system for cinnamaldehyde

dc.authorid0000-0001-8638-1198en_US
dc.authorid0000-0003-4965-8754en_US
dc.authorscopusid57434787900en_US
dc.authorscopusid25230307000en_US
dc.authorwosid-en_US
dc.authorwosidJ-6910-2012en_US
dc.contributor.authorYeldir, Elif Karacan
dc.contributor.authorOral, Ayhan
dc.date.accessioned2023-07-24T12:20:17Z
dc.date.available2023-07-24T12:20:17Z
dc.date.issued2021en_US
dc.departmentFakülteler, Fen Fakültesi, Kimya Bölümü
dc.description.abstractChitosan, a biodegradable and biocompatible polysaccharide, is a biopolymer with high potential for biomedical applications. In the scope of this study, chitosan microcapsules were prepared via a green method, without using any surfactants or crosslinkers. Cinnamaldehyde encapsulated microspheres were obtained by the same method and characterized by FTIR spectroscopy, XRD spectroscopy, and SEM. The release study of encapsulated cinnamaldehyde was carried out in a pH 7.4 phosphate buffered saline (PBS) at 37 °C. The amount of cinnamaldehyde released was analyzed using UV-Vis spectroscopy and GC/MS-MS. Accordingly, it was found that 350 mg of cinnamaldehyde was encapsulated per gram of chitosan, and the maximum amount of cinnamaldehyde released into the PBS medium was about 8 ppm. In addition, the release was seen to continue when the buffer was renewed. It is thought that the obtained cinnamaldehyde encapsulated chitosan microspheres could be used as a sustained release system.en_US
dc.identifier.citationYeldir, E. K., & Oral, A. (2021). Environmentally-friendly preparation of chitosan microspheres and encapsulation studies of cinnamaldehyde: Тowards convenient sustained release system for cinnamaldehyde. Macedonian Journal of Chemistry and Chemical Engineering, 40(2), 253-261. doi:10.20450/MJCCE.2021.2407en_US
dc.identifier.doi10.20450/MJCCE.2021.2407
dc.identifier.endpage261en_US
dc.identifier.issn1857-5552
dc.identifier.issn1857-5625
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85123849881
dc.identifier.startpage253en_US
dc.identifier.urihttps://doi.org/10.20450/MJCCE.2021.2407
dc.identifier.urihttps://hdl.handle.net/20.500.12428/4431
dc.identifier.volume40en_US
dc.identifier.wosWOS:000747339100005
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorYeldir, Elif Karacan
dc.institutionauthorOral, Ayhan
dc.language.isoen
dc.publisherMacedonian Journal of Chemistry and Chemical Engineeringen_US
dc.relation.ispartofMacedonian Journal of Chemistry and Chemical Engineeringen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution-NonCommercial 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/us/*
dc.subjectChitosanen_US
dc.subjectCinnamaldehydeen_US
dc.subjectMicrospheresen_US
dc.subjectSustained releaseen_US
dc.titleEnvironmentally-friendly preparation of chitosan microspheres and encapsulation studies of cinnamaldehyde: ?owards convenient sustained release system for cinnamaldehyde
dc.typeArticle

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