Anti-Staphylococcal Activity of Verbascum thapsus L. against Methicillin-Resistant Staphylococcus aureus

Objective: In this study, it was aimed to investigate the anti-Staphylococcal activity of ethanol extract obtained from leaves of Verbascum thapsus L. (Scrophulariaceae) plant. Methods: The anti-Staphylococcal activity of the extract of ethanol extracted from the leaves of Verbascum thapsus L. (Scrophulariaceae) was investigated against Methicillin-Resistant Staphylococcus aureus (MRSA) bacteria by Agarwell diffusion method and microdilution method. Results: The ethanol extract showed antibacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA) strains (MIC < 1024 mu g/mL). When compared with Methicillin and Gentamicin, the extract was more effective against MRSA strains. Conclusion: The use of Verbascum thapsus L. (Scrophulariaceae) as an anti-Staphylococcal agent has been found to be appropriate in vitro and should be performed in vivo.