Effect of Fetal Sex on Apoptosis-Regulating Proteins in Trophoblasts of Full-Term Human Placenta

Basit Öğe Kaydı
dc.contributor.authorGol, Mert
dc.contributor.authorTuna, Burcin
dc.date.accessioned2025-01-27T20:38:37Z
dc.date.available2025-01-27T20:38:37Z
dc.date.issued2008
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: Pregnant women with female fetuses have higher maternal serum human chorionic gonadotropin (hCG) levels compared to those pregnant women with male fetuses. Apoptosis in the placenta has a role in hCG secretion. In the present study, we examined the effect of fetal gender on apoptosis-regulating proteins in the trophoblast cells of human term placenta. Study Design: 34 uncomplicated, singleton, term pregnancies, 17 had male and 17 had female fetuses, were recruited in the study. Apoptosis-regulating proteins of the trophoblast cells were measured by using immunohistochemistry for Bcl-2 and Bax. Staining index values were compared between the female and male pregnancies. Results: There were no sex differences in Bcl-2 and Bax proteins. There were no correlations between maternal serum and cord blood hCG levels, and staining index values of two proteins in trophoblast cells. Conclusions: The difference in maternal serum and cord blood hCG levels in correlation with fetal sex is not associated with apoptosis-regulating proteins in the trophoblast cells of human term placenta. Copyright (C) 2008 S. Karger AG, Basel
dc.identifier.doi10.1159/000161570
dc.identifier.endpage56
dc.identifier.issn0378-7346
dc.identifier.issn1423-002X
dc.identifier.issue1
dc.identifier.pmid18843185
dc.identifier.scopus2-s2.0-53249090676
dc.identifier.scopusqualityQ2
dc.identifier.startpage53
dc.identifier.urihttps://doi.org/10.1159/000161570
dc.identifier.urihttps://hdl.handle.net/20.500.12428/23673
dc.identifier.volume67
dc.identifier.wosWOS:000261292400011
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherKarger
dc.relation.ispartofGynecologic and Obstetric Investigation
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectFetal gender
dc.subjecthCG
dc.subjectBcl-2
dc.subjectBax
dc.titleEffect of Fetal Sex on Apoptosis-Regulating Proteins in Trophoblasts of Full-Term Human Placenta
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu