Anthocyanins: Targeting of Signaling Networks in Cancer Cells

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dc.authoridFarooqi, Ammad/0000-0003-2899-5014
dc.contributor.authorSehitoglu, Muserref Hilal
dc.contributor.authorFarooqi, Ammad Ahmad
dc.contributor.authorQureshi, Muhammad Zahid
dc.contributor.authorButt, Ghazala
dc.contributor.authorAras, Aliye
dc.date.accessioned2025-01-27T20:26:55Z
dc.date.available2025-01-27T20:26:55Z
dc.date.issued2014
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractIt is becoming progressively more understandable that phytochemicals derived from edible plants have shown potential in modelling their interactions with their target proteins. Rapidly accumulating in-vitro and in- vivo evidence indicates that anthocyanins have anticancer activity in rodent models of cancer. More intriguingly, evaluation of bilberry anthocyanins as chemopreventive agents in twenty-five colorectal cancer patients has opened new window of opportunity in translating the findings from laboratory to clinic. Confluence of information suggests that anthocyanins treated cancer cells reveal up-regulation of tumor suppressor genes. There is a successive increase in the research-work in nutrigenomics and evidence has started to shed light on intracellular-signaling cascades as common molecular targets for anthocyanins. In this review we bring to limelight how anthocyanins induced apoptosis in cancer cells via activation of extrinsic and intrinsic pathways.
dc.identifier.doi10.7314/APJCP.2014.15.5.2379
dc.identifier.endpage2381
dc.identifier.issn1513-7368
dc.identifier.issue5
dc.identifier.pmid24716988
dc.identifier.scopus2-s2.0-84899065088
dc.identifier.scopusqualityQ3
dc.identifier.startpage2379
dc.identifier.urihttps://doi.org/10.7314/APJCP.2014.15.5.2379
dc.identifier.urihttps://hdl.handle.net/20.500.12428/22496
dc.identifier.volume15
dc.identifier.wosWOS:000335651200083
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAsian Pacific Organization Cancer Prevention
dc.relation.ispartofAsian Pacific Journal of Cancer Prevention
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectApoptosis
dc.subjectanthocyanins
dc.subjectsignaling
dc.subjectcancer
dc.titleAnthocyanins: Targeting of Signaling Networks in Cancer Cells
dc.typeEditorial

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