Identifying early left atrial dysfunction in COPD patients using ECG morphology-voltage-P wave duration score

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dc.contributor.authorKüçük, Uğur
dc.contributor.authorMutlu, Pınar
dc.contributor.authorMirici, Arzu
dc.contributor.authorÖzpınar, Uğur
dc.contributor.authorÖzpınar, Selin Beyza
dc.date.accessioned2025-01-27T18:53:30Z
dc.date.available2025-01-27T18:53:30Z
dc.date.issued2025
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBackground: Chronic Obstructive Pulmonary Disease (COPD) is associated with left atrial (LA) dyfunction, which may contribute to adverse cardiovascular outcomes. This study investigates the predictive value of lately identified morphology-voltage-P wave duration electrocardiography (MVP ECG) score for detecting early LA dysfunction in COPD patients. Methods: In this cross-sectional study, 101 COPD patients were enrolled. All patients underwent speckle tracking echocardiography and were classified into two groups based on their LA functions. Results: Our findings demonstrate significant variations in Peak Atrial Longitudinal Strain (PALS) values among COPD patients, with a mean PALS of 28.74 ± 1.81 % for the group with normal LA function and 18.44 ± 1.87 % for the group with abnormal LA function (p < 0.001). Despite similar LA diameters across groups, these variations indicate subclinical LA pathogenesis. ROC curve analysis indicated that an MVP ECG score greater than 2.5 predicted abnormal LA function with a sensitivity of 65 % and a specificity of 91 % (area under the curve [AUC]: 0.873; p < 0.001), suggesting its utility in identifying atrial damage and remodeling. Conclusions: The MVP ECG score shows promise as a tool for early detection of atrial remodeling in COPD patients. © 2024 Elsevier Inc.
dc.identifier.doi10.1016/j.jelectrocard.2024.153854
dc.identifier.issn0022-0736
dc.identifier.pmid39721368
dc.identifier.scopus2-s2.0-85212831288
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.1016/j.jelectrocard.2024.153854
dc.identifier.urihttps://hdl.handle.net/20.500.12428/12734
dc.identifier.volume88
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier B.V.
dc.relation.ispartofJournal of Electrocardiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_Scopus_20250125
dc.subject12?lead electrocardiogram; Left atrial function; Strain echocardiography
dc.titleIdentifying early left atrial dysfunction in COPD patients using ECG morphology-voltage-P wave duration score
dc.typeArticle

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