Identifying early left atrial dysfunction in COPD patients using ECG morphology-voltage-P wave duration score

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dc.authoridKüçük, Uğur / 0000-0003-4669-7387
dc.authoridMutlu, Pınar / 0000-0002-7496-0026
dc.authoridMirici, Arzu / 0000-0002-7189-9258
dc.authoridÖzpınar, Uğur / 0000-0001-6119-9031
dc.authoridÖzpınar, Selin Beyza / 0009-0008-2785-7879
dc.contributor.authorKüçük, Uğur
dc.contributor.authorMutlu, Pınar
dc.contributor.authorMirici, Arzu
dc.contributor.authorÖzpınar, Uğur
dc.contributor.authorÖzpınar, Selin Beyza
dc.date.accessioned2025-01-27T18:53:30Z
dc.date.available2025-01-27T18:53:30Z
dc.date.issued2025
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBackground Chronic Obstructive Pulmonary Disease (COPD) is associated with left atrial (LA) dyfunction, which may contribute to adverse cardiovascular outcomes. This study investigates the predictive value of lately identified morphology-voltage-P wave duration electrocardiography (MVP ECG) score for detecting early LA dysfunction in COPD patients. Methods In this cross-sectional study, 101 COPD patients were enrolled. All patients underwent speckle tracking echocardiography and were classified into two groups based on their LA functions. Results Our findings demonstrate significant variations in Peak Atrial Longitudinal Strain (PALS) values among COPD patients, with a mean PALS of 28.74 ± 1.81 % for the group with normal LA function and 18.44 ± 1.87 % for the group with abnormal LA function (p < 0.001). Despite similar LA diameters across groups, these variations indicate subclinical LA pathogenesis. ROC curve analysis indicated that an MVP ECG score greater than 2.5 predicted abnormal LA function with a sensitivity of 65 % and a specificity of 91 % (area under the curve [AUC]: 0.873; p < 0.001), suggesting its utility in identifying atrial damage and remodeling. Conclusions The MVP ECG score shows promise as a tool for early detection of atrial remodeling in COPD patients.
dc.identifier.doi10.1016/j.jelectrocard.2024.153854
dc.identifier.issn0022-0736
dc.identifier.pmid39721368
dc.identifier.scopus2-s2.0-85212831288
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.1016/j.jelectrocard.2024.153854
dc.identifier.urihttps://hdl.handle.net/20.500.12428/12734
dc.identifier.volume88
dc.identifier.wosWOS:001405175500001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherElsevier B.V.
dc.relation.ispartofJournal of Electrocardiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_Scopus_20250125
dc.subjectStrain echocardiography
dc.subject12‑lead electrocardiogram
dc.subjectLeft atrial function
dc.titleIdentifying early left atrial dysfunction in COPD patients using ECG morphology-voltage-P wave duration score
dc.typeArticle

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