Characteristics of hospitalised COVID-19 patients and parameters associated with severe pneumonia

dc.authorid0000-0002-7189-9258en_US
dc.authorscopusid6507027912en_US
dc.authorwosidFOM-2549-2022en_US
dc.contributor.authorTuran, Onur
dc.contributor.authorMirici, Arzu
dc.contributor.authorDuru Akçalı, Serap
dc.contributor.authorTuran, Pakize Ayşe
dc.contributor.authorBatum, Özgür
dc.contributor.authorŞengül, Aysun
dc.date.accessioned2023-04-17T11:22:33Z
dc.date.available2023-04-17T11:22:33Z
dc.date.issued2021en_US
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractBackground: After the first case of coronavirus disease 2019 (COVID-19) was reported in China in December 2019, it caused a global pandemic, including Turkey. Objectives: The aim of this study was to analyse the characteristics of hospitalised COVID-19 patients and assess the parameters related to severe pneumonia. Methods: Included in the study were hospitalised COVID-19 patients with positive naso-oropharyngeal swabs. Patients’ demographics, admission symptoms, laboratory and radiological findings were recorded retrospectively. Results: Of 1013 patients, 583 were males (57.6%) and 430 were females (42.4%), with a mean age of 53.7 ± 17.9. More than half of the patients had at least one comorbidities, the most common of which were hypertension and diabetes mellitus. Cough (59.8%), fatigue (49.5%) and fever (41.2%) were the most common presenting symptoms. Of the hospitalised COVID-19 patients, 84.9% had pneumonia and 83.5% had typical radiological COVID-19 appearances (94.5%: ground-glass areas). The most common laboratory findings were high C-reactive protein (CRP) (73.6%) and lactate dehydrogenase (LDH) (46.2%) levels, as well as lymphopenia (30.1%). Severe pneumonia was present in 28.1% of COVID-19 patients. Multivariate logistic regression analysis indicated that advanced age, hypotension, anaemia and elevated CRP and LDH serum levels were independent risk factors for the severity of COVID-19 pneumonia (P =.011,.006,.017,.003 and.001, respectively). Conclusion: This study, as one of the first multicentre studies about characteristics of COVID-19 in Turkey, may guide about disease-related parameters and severity of pneumonia. Age, blood pressure, complete blood count and routine biochemical tests (including CRP and LDH) would appear to be important parameters for the evaluation of the severity of COVID-19 pneumonia.en_US
dc.identifier.citationTuran, O., Mirici, A., Duru Akçalı, S., Turan, P. A., Batum, Ö., Şengül, A., . . . Yilmaz, Ü. (2021). Characteristics of hospitalised COVID-19 patients and parameters associated with severe pneumonia. International Journal of Clinical Practice, 75(11) doi:10.1111/ijcp.14786en_US
dc.identifier.doi10.1111/ijcp.14786
dc.identifier.issn1368-5031
dc.identifier.issn1742-1241
dc.identifier.issue11en_US
dc.identifier.pmid34480831
dc.identifier.scopus2-s2.0-85114864808
dc.identifier.urihttps://doi.org/10.1111/ijcp.14786
dc.identifier.urihttps://hdl.handle.net/20.500.12428/4010
dc.identifier.volume75en_US
dc.identifier.wosWOS:000695863400001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorMirici, Arzu
dc.language.isoen
dc.publisherJohn Wiley & Sons Ltden_US
dc.relation.ispartofInternational Journal of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectC reactive proteinen_US
dc.subjectCOVID-19en_US
dc.subjectRetrospective Studiesen_US
dc.subjectSARS-CoV-2en_US
dc.subjectPneumoniaen_US
dc.titleCharacteristics of hospitalised COVID-19 patients and parameters associated with severe pneumonia
dc.typeArticle

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