CAN DIFFUSION WEIGHTED MAGNETIC RESONANCE IMAGING DIFFERENTIATE BETWEEN INFLAMMATORY-INFECTIOUS AND MALIGNANT PLEURAL EFFUSIONS?

dc.authoridGedik, Ismail Ertugrul/0000-0002-1667-4793
dc.authoridGonlugur, Ugur/0000-0001-8720-2788
dc.authoridKaratag, Ozan/0000-0002-0606-6364
dc.contributor.authorKaratag, O.
dc.contributor.authorAlar, T.
dc.contributor.authorKosar, S.
dc.contributor.authorOcakoglu, G.
dc.contributor.authorYildiz, Y.
dc.contributor.authorGedik, E.
dc.contributor.authorGonlugur, U.
dc.date.accessioned2025-01-27T20:41:37Z
dc.date.available2025-01-27T20:41:37Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractAim: To assess exudative pleural effusions with diffusion-weighted magnetic resonance imaging (DW-MRI) in order to determine non-invasive differentiation criteria for inflammatory-infectious and malignant effusions. Materials and methods: Thirty-two patients with pleural effusions underwent DW-MRI with 4 different b values (10, 500, 750 and 1000 s/mm(2)). ADC maps were generated automatically. Signal intensity and ADC values were measured. Following MRI, pleural fluid of 10-15 ml was obtained and analyzed. AUC values were compared for different diffusion levels of ADC and SI measurements. The relationship between ADC values and pleural effusion LDH and total protein levels was examined. Results: The cut-off values obtained from signal intensity and ADC measurements to differentiate exudates with malignant pathology were not found to be statistically significant. In the inflammatory-infectious group, a significant negative correlation was observed between ADC values and pleural fluid LDH measurements in all b values. In the malignant group, a significant positive correlation was observed between ADC values and pleural fluid total protein measurements in b values of 500 and 1000. Conclusion:Infectious/inflammatory and malignant effusions overlap strongly and cannot therefore be differentiated using DW MRI.
dc.identifier.doi10.5334/jbr-btr.767
dc.identifier.endpage67
dc.identifier.issn1780-2393
dc.identifier.issue2
dc.identifier.pmid30394441
dc.identifier.scopus2-s2.0-85000797786
dc.identifier.scopusqualityN/A
dc.identifier.startpage63
dc.identifier.urihttps://doi.org/10.5334/jbr-btr.767
dc.identifier.urihttps://hdl.handle.net/20.500.12428/24192
dc.identifier.volume98
dc.identifier.wosWOS:000361265800001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAssoc Royal Soc Scientifiques Medicales Belges
dc.relation.ispartofJbr-Btr
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectLung
dc.subjecteffusion - Lung
dc.subjectMR - Magnetic resonance (MR)
dc.subjectdiffusion study
dc.titleCAN DIFFUSION WEIGHTED MAGNETIC RESONANCE IMAGING DIFFERENTIATE BETWEEN INFLAMMATORY-INFECTIOUS AND MALIGNANT PLEURAL EFFUSIONS?
dc.typeArticle

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