Evaluation of craniofacial anthropometry of children with ?-thalassemia major in the eastern Anatolia: a case-control study

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dc.authoridGenc, Celal/0000-0003-4037-9783
dc.contributor.authorGenc, Cigdem cetin
dc.contributor.authorGenc, Celal
dc.contributor.authorYenigurbuz, Fatma Demir
dc.date.accessioned2025-01-27T20:20:20Z
dc.date.available2025-01-27T20:20:20Z
dc.date.issued2023
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective The present study aims to compare beta-thalassemia major patients and healthy individuals in terms of anthropometric characteristics and changes in craniofacial profile. Subjects and method Craniofacial anthropometric measurements were performed on a total of 422 subjects (199 beta-thalassemia major patients and 223 healthy individuals) by using a millimetric caliper and tape measure on 19 anthropometric parameters (8 horizontal, 10 vertical, and 1 head circumference) in cranial, facial, nasal, orolabial, and orbital zones. Results The difference between the orbital, nasal, and orolabial zone parameters of healthy subjects and beta-thalassemia major patients was found to be statistically significant (p < 0.05). There was no statistically significant difference between the groups in terms of head circumference in the cranial zone and total facial height in facial zone (n- gn) values ( p>0.05). In intragroup comparison between females and males with beta-thalassemia, statistically significant differences were found in forehead width (ft-ft), forehead height (tr-gl), right eye width ( R ex-ex), and upper lip height (sn-stm) (p < 0.05). Conclusion Understanding the craniofacial profile changes in beta-thalassemia major patients and increasing our knowledge about the relationship between the course and severity of disease and the level of these changes would contribute to the advancements in diagnoses to be made in facial and jaw zones of these patients and in the treatment plans. Clinical relevance We believe that the analysis and results of the craniofacial anthropometric data obtained in the study will contribute to the diagnosis and treatment processes of patients with beta-thalassemia major in areas of expertise such as craniofacial surgery, orthodontics, and hemato-oncology.
dc.identifier.doi10.1007/s00784-023-05191-z
dc.identifier.endpage5803
dc.identifier.issn1432-6981
dc.identifier.issn1436-3771
dc.identifier.issue10
dc.identifier.pmid37548765
dc.identifier.scopus2-s2.0-85166926950
dc.identifier.scopusqualityQ1
dc.identifier.startpage5793
dc.identifier.urihttps://doi.org/10.1007/s00784-023-05191-z
dc.identifier.urihttps://hdl.handle.net/20.500.12428/21670
dc.identifier.volume27
dc.identifier.wosWOS:001044372200002
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer Heidelberg
dc.relation.ispartofClinical Oral Investigations
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectbeta-Thalassemia major
dc.subjectCraniofacial parameters
dc.subjectAnthropometry
dc.subjectFacial analysis
dc.titleEvaluation of craniofacial anthropometry of children with ?-thalassemia major in the eastern Anatolia: a case-control study
dc.typeArticle

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