Awareness of Hepatitis B Virus Reactivation Among Physicians Administering Immunosuppressive Treatment and Related Clinical Practices

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dc.authoridUral, Onur/0000-0003-1355-7572
dc.authoridSumer, Sua/0000-0003-3508-7516
dc.authoridHaykir Solay, Asli/0000-0002-1326-9776
dc.authoridHakyemez, Ismail Necati/0000-0001-6133-9604
dc.authoridToka, Onur/0000-0002-4025-4537
dc.authoridTulek, Necla/0000-0002-3952-4982
dc.authoridAktug Demir, Nazlim/0000-0002-4703-0827
dc.contributor.authorKorkmaz, Pinar
dc.contributor.authorDemirturk, Nese
dc.contributor.authorAydin, Gule
dc.contributor.authorCeken, Sabahat
dc.contributor.authorAygen, Bilgehan
dc.contributor.authorToka, Onur
dc.contributor.authorGundogdu, Kiymet
dc.date.accessioned2025-01-27T20:56:29Z
dc.date.available2025-01-27T20:56:29Z
dc.date.issued2019
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: This study aimed to evaluate the awareness and knowledge levels of all physicians administering immunosuppressive treatment concerning hepatitis B virus (HBV) reactivation, and draw attention to the importance of the subject through evaluation. Methods: The study was carried out by infectious diseases and clinical microbiology specialists in 37 health centers, and it was performed in Turkey between January and March 2017. All specialists providing a written consent and working in the departments of Medical Oncology, Hematology, Dermatology and Venereology, Physical Medicine and Rehabilitation, and Rheumatology of each study center were included in the study. Results: A total of 430 physicians participated in the study. Their mean age was 39.87 +/- 7.42 years, and 47.9% of them were males. During their career, 39.3% of these physicians had encountered patients developing HBV reactivation while receiving immunosuppressive treatment. The rate of encountering patients who died due to HBV reactivation was 6.5%. 97% of physicians who participated, considered the risk of HBV reactivation to be important. 70.2% of physicians stated that guidelines related to HBV reactivation and antiviral treatment for these patients were discussed in the congresses they participated, regarding their specialties. The rate of performing hepatitis screening among physicians whose patients developed HBV reactivation was statistically significantly higher than those physicians who had no patients with HBV reactivation (p<0.05). Physicians who used the guidelines related to HBV reactivation in their specialties performed screening for the HBV infection much more often than physicians who did not use the guidelines (p=0.002). Conclusions: According to the results obtained in our study, the rates of conducting screening and awareness of HBV reactivation among physicians administering immunosuppressive treatment were higher compared with similar studies; however, their awareness that HBV DNA and anti-HBc should be utilized much more frequently among the serological tests they use for screening of HBV infection, should be increased.
dc.identifier.doi10.5152/kd.2019.33
dc.identifier.endpage153
dc.identifier.issn1301-143X
dc.identifier.issn1309-1484
dc.identifier.issue2
dc.identifier.scopus2-s2.0-85070991417
dc.identifier.scopusqualityQ4
dc.identifier.startpage146
dc.identifier.urihttps://doi.org/10.5152/kd.2019.33
dc.identifier.urihttps://hdl.handle.net/20.500.12428/26414
dc.identifier.volume32
dc.identifier.wosWOS:000481718600008
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isotr
dc.publisherAves
dc.relation.ispartofKlimik Journal
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectHepatitis B
dc.subjectimmunosuppression
dc.subjectreactivation
dc.titleAwareness of Hepatitis B Virus Reactivation Among Physicians Administering Immunosuppressive Treatment and Related Clinical Practices
dc.title.alternativeİmmünosüpresif tedavi veren hekimlerin hepatit b virusu reaktivasyonuyla ilgili farkındalıklarının ve klinik pratiklerinin değerlendirilmesi
dc.typeArticle

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