Lateral flow assays for viruses diagnosis: Up-to-date technology and future prospects

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dc.contributor.authorInce, Bahar
dc.contributor.authorSezgintuerk, Mustafa Kemal
dc.date.accessioned2025-01-27T20:35:08Z
dc.date.available2025-01-27T20:35:08Z
dc.date.issued2022
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBacteria, viruses, and parasites are harmful microorganisms that cause infectious diseases. Early detec-tion of diseases is critical to prevent disease transmission and provide epidemic preparedness, as these can cause widespread deaths and public health crises, particularly in resource-limited countries. Lateral flow assay (LFA) systems are simple-to-use, disposable, inexpensive diagnostic devices to test biomarkers in blood and urine samples. Thus, LFA has recently received significant attention, especially during the pandemic. Here, first of all, the design principles and working mechanisms of existing LFA methods are examined. Then, current LFA implementation strategies are presented for communicable disease di-agnoses, including COVID-19, zika and dengue, HIV, hepatitis, influenza, malaria, and other pathogens. Furthermore, this review focuses on an overview of current problems and accessible solutions in detecting infectious agents and diseases by LFA, focusing on increasing sensitivity with various detection methods. In addition, future trends in LFA-based diagnostics are envisioned.(c) 2022 Elsevier B.V. All rights reserved.
dc.identifier.doi10.1016/j.trac.2022.116725
dc.identifier.issn0165-9936
dc.identifier.issn1879-3142
dc.identifier.pmid35815063
dc.identifier.scopus2-s2.0-85135102823
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1016/j.trac.2022.116725
dc.identifier.urihttps://hdl.handle.net/20.500.12428/23578
dc.identifier.volume157
dc.identifier.wosWOS:000835334200006
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Sci Ltd
dc.relation.ispartofTrac-Trends in Analytical Chemistry
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectLateral flow assay
dc.subjectViruses detection
dc.subjectSARS-CoV-2
dc.subjectBiosensor
dc.subjectImmunoassay
dc.titleLateral flow assays for viruses diagnosis: Up-to-date technology and future prospects
dc.typeReview Article

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