Is cognitive processing affected in adults with hypospadias?: P300 study

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dc.authoridTekeli, Hakan/0000-0003-3274-2765
dc.authoridAlan, Cabir/0000-0002-6024-4475
dc.contributor.authorTekeli, Hakan
dc.contributor.authorKocoglu, Hasan
dc.contributor.authorAlan, Cabir
dc.contributor.authorTavsanli, Mustafa Emir
dc.contributor.authorYasar, Halit
dc.contributor.authorMalkoc, Ercan
dc.contributor.authorKendirli, Mustafa Tansel
dc.date.accessioned2025-01-27T20:22:58Z
dc.date.available2025-01-27T20:22:58Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBackground: Hypospadias is a common urogenital system disorder. The frenulum, which is the most sensitive area of the glans penis, is not present in patients with hypospadias. This may lead to a failure in sexual and ejaculatory function, and cause emotional problems affecting cognitive processes. Aim: We aimed to study auditory Event Related Potentials (ERP) in patients with hypospadias to understand the status of cognitive function. Materials and Methods: Seventeen patients with hypospadias who presented to the Urology Outpatient Clinic of anakkale Military Hospital, and 11 healthy individuals of similar age were chosen. The auditory oddball paradigm with ERP from the Cz and Fz head regions were studied. The latency and amplitude of the P300 wave were measured. Results: Both, the study and control groups consisted of young males. Although the study group had a longer P300 latency and lower P300 amplitude when compared to control group, the results were not statistically significant (p: 0.059 and 0.346 respectively). Conclusion: Although the results are not statistically significant, our findings indicate that there may be cognitive changes in patients with hypospadias. Further studies of larger sample size and older patient cohorts are needed.
dc.identifier.doi10.1515/med-2015-0059
dc.identifier.endpage363
dc.identifier.issn2391-5463
dc.identifier.issue1
dc.identifier.pmid28352719
dc.identifier.scopus2-s2.0-84946564274
dc.identifier.scopusqualityQ2
dc.identifier.startpage359
dc.identifier.urihttps://doi.org/10.1515/med-2015-0059
dc.identifier.urihttps://hdl.handle.net/20.500.12428/22084
dc.identifier.volume10
dc.identifier.wosWOS:000371696900036
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherDe Gruyter Poland Sp Z O O
dc.relation.ispartofOpen Medicine
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectHypospadias
dc.subjectEvent Related Potentials-P300
dc.subjectCognition
dc.titleIs cognitive processing affected in adults with hypospadias?: P300 study
dc.typeArticle

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