A Self-Powered Enzymatic Glucose Sensor Utilizing Bimetallic Nanoparticle Composites Modified Pencil Graphite Electrodes as Cathode

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dc.authoridEmir, Gamze/0000-0002-3976-2243
dc.authoridDilgin, Yusuf/0000-0002-2980-6871
dc.contributor.authorEmir, Gamze
dc.contributor.authorDilgin, Yusuf
dc.contributor.authorSahin, Samet
dc.contributor.authorAkgul, Cahit
dc.date.accessioned2025-01-27T20:16:36Z
dc.date.available2025-01-27T20:16:36Z
dc.date.issued2024
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractEnzymatic biofuel cells (EBFC) are promising sources of green energy owing to the benefits of using renewable biofuels, eco-friendly biocatalysts, and moderate operating conditions. In this study, a simple and effective EBFC was presented using an enzymatic composite material-based anode and a nonenzymatic bimetallic nanoparticle-based cathode respectively. The anode was constructed from a glassy carbon electrode (GCE) modified with a multi-walled carbon nanotube (MWCNT) and ferrocene (Fc) as a conductive layer coupled with the enzyme glucose oxidase (GOx) as a sensitive detection layer for glucose. A chitosan layer was also applied to the electrode as a protective layer to complete the composite anode. Chronoamperometry (CA) results show that the MWCNT-Fc-GOx/GCE electrode has a linear relationship between current and glucose concentration, which varied from 1 to 10 mM. The LOD and LOQ were calculated for anode as 0.26 mM and 0.87 mM glucose, respectively. Also the sensitivity of the proposed sensor was calculated as 25.71 mu\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\mu$$\end{document}A/mM. Moreover, the studies of some potential interferants show that there is no significant interference for anode in the determination of glucose except ascorbic acid (AA), uric acid (UA), and dopamine (DA). On the other hand, the cathode consisted of a disposable pencil graphite electrode (PGE) modified with platinum-palladium bimetallic nanoparticles (Nps) which exhibit excellent conductivity and electron transfer rate for the oxygen reduction reaction (ORR). The constructed EBFC was optimized and characterized using various electroanalytical techniques. The EBFC consisting of MWCNT-Fc-GOx/GCE anode and Pt-PdNps/PGE cathode exhibits an open circuit potential of 285.0 mV and a maximum power density of 32.25 mu W cm-2 under optimized conditions. The results show that the proposed EBFC consisting of an enzymatic composite-based anode and bimetallic nanozyme-based cathode is a unique design and a promising candidate for detecting glucose while harvesting power from glucose-containing natural or artificial fluids.
dc.description.sponsorshipScientific Research Projects Coordination Unit of Canakkale Onsekiz Mart University [FDK-2022-4073]
dc.description.sponsorshipWe appreciate the Scientific Research Projects Coordination Unit of Canakkale Onsekiz Mart University (FDK-2022-4073) for financial support. This study was produced as a part of the PhD thesis of Gamze Emir GUNAY.
dc.identifier.doi10.1007/s12010-024-05068-1
dc.identifier.issn0273-2289
dc.identifier.issn1559-0291
dc.identifier.pmid39331328
dc.identifier.scopus2-s2.0-85205033559
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1007/s12010-024-05068-1
dc.identifier.urihttps://hdl.handle.net/20.500.12428/21311
dc.identifier.wosWOS:001324514300003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofApplied Biochemistry and Biotechnology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectEnzymatic biofuel cell (EBFC)
dc.subjectGlucose oxidase (GOx)
dc.subjectNanozyme
dc.subjectSelf-powered glucose sensor (SPGS)
dc.subjectFerrocene (Fc)
dc.subjectBimetallic nanoparticles
dc.titleA Self-Powered Enzymatic Glucose Sensor Utilizing Bimetallic Nanoparticle Composites Modified Pencil Graphite Electrodes as Cathode
dc.typeArticle

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