Decreased circulatory erythropoietin in hyperacute phase of myocardial ischemia

Basit Öğe Kaydı
dc.authoridErcan, Ertugrul/0000-0003-0480-4738
dc.authoridTURK, UGUR ONSEL/0000-0001-6348-6616
dc.contributor.authorAlioglu, Emin
dc.contributor.authorErcan, Ertugrul
dc.contributor.authorTamer, Gulden Sonmez
dc.contributor.authorDuman, Can
dc.contributor.authorTurk, Ugur
dc.contributor.authorTengiz, Istemihan
dc.contributor.authorTuzun, Nurullah
dc.date.accessioned2025-01-27T20:54:21Z
dc.date.available2025-01-27T20:54:21Z
dc.date.issued2011
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractPurpose: Erythropoietin provides cellular protection by inhibiting apoptosis. Myocardial damage related to the cardiac ischemia is more prominent especially in the first 6 h. In the present study, circulatory erythropoietin levels in response to cardiac ischemia were evaluated. Materials and methods: Patients with stable angina who underwent balloon angioplasty (study group, n = 55) and hospitalized for coronary angiography (as control group, n = 23) were enrolled into the study. Serum erythropoietin levels were measured in both groups in baseline, 6 and 18 h after the procedure. Results: Coronary balloon inflation time was accepted as duration of myocardial ischemia. Study group showed significant erythropoietin reduction at sixth hour compared to control group. Erythropoietin reduction at sixth hour was significantly correlated with duration of myocardial ischemia. Conclusion: Decreased circulatory erythropoietin levels in the early phase of acute cardiac ischemia may accelerate the apoptotic activity. Recombinant erythropoietin replacement to prevent erythropoietin decrease following cardiac ischemia may have negative effect on myocyte loss. (C) 2008 Elsevier Ireland Ltd. All rights reserved.
dc.identifier.doi10.1016/j.ijcard.2008.12.184
dc.identifier.endpageE52
dc.identifier.issn0167-5273
dc.identifier.issue3
dc.identifier.pmid19171391
dc.identifier.scopus2-s2.0-78951473195
dc.identifier.scopusqualityQ1
dc.identifier.startpageE49
dc.identifier.urihttps://doi.org/10.1016/j.ijcard.2008.12.184
dc.identifier.urihttps://hdl.handle.net/20.500.12428/26053
dc.identifier.volume146
dc.identifier.wosWOS:000286460500001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Ireland Ltd
dc.relation.ispartofInternational Journal of Cardiology
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectErythropoietin
dc.subjectIschemia
dc.subjectApoptosis
dc.titleDecreased circulatory erythropoietin in hyperacute phase of myocardial ischemia
dc.typeLetter

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu