Does topical use of autologous serum help to reduce post-tonsillectomy morbidity? A prospective, controlled preliminary study

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dc.authoridAylanc, Hakan/0000-0002-8907-3809
dc.authoridAltinisik, Hatice Betul/0000-0001-9273-0876
dc.contributor.authorKara, M.
dc.contributor.authorErdogan, H.
dc.contributor.authorAltinisik, H. B.
dc.contributor.authorAylanc, H.
dc.contributor.authorGuclu, O.
dc.contributor.authorDerekoy, F. S.
dc.date.accessioned2025-01-27T20:54:13Z
dc.date.available2025-01-27T20:54:13Z
dc.date.issued2016
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBackground: To evaluate the effects of autologous serum usage on throat pain, haemorrhage and tonsillar fossa epithelisation in patients after tonsillectomy. Methods: Thirty-two patients (aged 4-15 years) were included in the study. Tonsillectomy was performed and autologous serum was administered topically to the right tonsillar fossa during the operation, and at 8 and 24 hours post-operatively. The left side served as the control. A visual analogue scale was used to record the patient's pain every day. Each patient's oropharynx was observed on the 5th and 10th post-operative days to examine bleeding and epithelisation. Results: The pain scores for the side administered autologous serum were significantly lower than those for the control side, on the night following the operation and on the 1st, 2nd, 5th and 6th post-operative days. Tonsillar fossa epithelisation was significantly accelerated on the study side compared with the control side on the 5th and 10th post-operative days. Conclusion: In tonsillectomy patients, topically administered autologous serum contributed to throat pain relief and tonsillar fossa epithelisation during the post-operative period.
dc.identifier.doi10.1017/S0022215116007970
dc.identifier.endpage668
dc.identifier.issn0022-2151
dc.identifier.issn1748-5460
dc.identifier.issue7
dc.identifier.pmid27210022
dc.identifier.scopus2-s2.0-84969751522
dc.identifier.scopusqualityQ2
dc.identifier.startpage662
dc.identifier.urihttps://doi.org/10.1017/S0022215116007970
dc.identifier.urihttps://hdl.handle.net/20.500.12428/26015
dc.identifier.volume130
dc.identifier.wosWOS:000382590700012
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherCambridge Univ Press
dc.relation.ispartofJournal of Laryngology and Otology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectTonsillectomy
dc.subjectSerum
dc.subjectPostoperative Pain
dc.subjectWound Healing
dc.subjectHemorrhage
dc.titleDoes topical use of autologous serum help to reduce post-tonsillectomy morbidity? A prospective, controlled preliminary study
dc.typeArticle

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