Serum resistin level: as a predictor of atrial fibrillation after coronary artery bypass graft surgery

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dc.authoridAyik, Mehmet Fatih/0000-0002-0780-3047
dc.contributor.authorGungor, Hasan
dc.contributor.authorAyik, Mehmet Fatih
dc.contributor.authorKirilmaz, Bahadir
dc.contributor.authorErtugay, Serkan
dc.contributor.authorGul, Ilker
dc.contributor.authorYildiz, Bekir Serhat
dc.contributor.authorNalbantgil, Sanem
dc.date.accessioned2025-01-27T20:23:13Z
dc.date.available2025-01-27T20:23:13Z
dc.date.issued2011
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractAim Atrial fibrillation (AF) is the most common arrhythmia with an incidence of 25-40%, after coronary artery bypass grafting (CABG). Resistin is a newly identified adipocyte-secreted hormone belonging to a cysteine-rich protein family. This study examined the relation of preoperative and postoperative early serum resistin level, which can play an important role as an inflammatory marker to predict AF after CABG. Methods We prospectively analyzed 40 consecutive patients (mean age, 59.2+10.3 years; 31 men and nine women) who were undergoing CABG between September and November 2009 at our department. Blood samples were taken to examine quantities of resistin level, the day before surgery and on the 24th hour in the intensive care unit. Results The incidence of AF was 25% (n=10, 2.2+1.1 days, 1.2+0.4 episodes). Preoperative resistin level was higher in the AF group (10.6+3.3 vs. 9.1+4.5 ng/ml, P=0.33), but it was not statistically significant. Postoperative resistin level was significantly higher in the AF group (27.4+8.4 vs. 17.9+9.1 ng/ml, P=0.012) compared with the sinus rhythm group. Resistin levels significantly increased after the surgery in both groups [9.1+4.5 vs. 17.9+9.1 ng/ml, P<0.001 (sinus rhythm group) and 10.6+3.3 vs. 27.4+8.4 ng/ml, P<0.001 (AF group)]. Conclusion Patients with an elevated postoperative resistin level may have high risk for AF after CABG. This intervention targeting inflammation might help reduce the incidence of AF. Coron Artery Dis 22:484-490 (C) 2011 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.
dc.identifier.doi10.1097/MCA.0b013e32834b67bb
dc.identifier.endpage490
dc.identifier.issn0954-6928
dc.identifier.issn1473-5830
dc.identifier.issue7
dc.identifier.pmid21915052
dc.identifier.scopus2-s2.0-80053622062
dc.identifier.scopusqualityQ3
dc.identifier.startpage484
dc.identifier.urihttps://doi.org/10.1097/MCA.0b013e32834b67bb
dc.identifier.urihttps://hdl.handle.net/20.500.12428/22149
dc.identifier.volume22
dc.identifier.wosWOS:000295621500006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofCoronary Artery Disease
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectatrial fibrillation
dc.subjectcoronary artery bypass graft surgery
dc.subjectinflammation
dc.subjectresistin
dc.titleSerum resistin level: as a predictor of atrial fibrillation after coronary artery bypass graft surgery
dc.typeArticle

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