Cord blood S100B levels in low-risk term pregnancies with meconium-stained amniotic fluid

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dc.authoridKiykac Altinbas, Sadiman/0000-0003-2773-9641
dc.contributor.authorHizli, Deniz
dc.contributor.authorAltinbas, Sadiman Kiykac
dc.contributor.authorKosus, Aydin
dc.contributor.authorKosus, Nermin
dc.contributor.authorUysal, Sema
dc.contributor.authorHacivelioglu, Servet
dc.contributor.authorGelisen, Orhan
dc.date.accessioned2025-01-27T20:38:45Z
dc.date.available2025-01-27T20:38:45Z
dc.date.issued2013
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: The aim of this study was to compare cord blood S100B levels and cord blood gas parameters of term infants with meconium-stained amniotic fluid (MSAF) to those infants with clear amniotic fluid. Methods: Term pregnant women at an active phase of labor and having MSAF were defined as the study group (n = 35) and pregnant women with clear amniotic fluid, and matched for age, parity, and gestational age were defined as the control group (n = 35). Cord blood S100B levels and gas parameters were measured. Results: LogS100B values of study and control groups were 2.40 +/- 0.21 and 2.43 +/- 0.29 pg/ml, respectively. The difference was not statistically significant (p = 0.675). LogS100B levels slightly increased as meconium thickened. (2.32 +/- 0.16, 2.41 +/- 0.17, and 2.44 +/- 0.28 pg/ml, respectively). However, no difference was found between groups (p = 0.438). Moreover, the study group had a statistically lower HCO3 level (21.80 vs 23.60 mmol/l) and a higher rate of base deficit (4.85 vs 3.25 mmol/l) than the control group. However, median HCO3 and base deficit values were within normal limits in both groups. Conclusion: The present study showed that cord blood S100B levels of infants born through MSAF were not different from those with clear amniotic fluid. This finding suggests that MSAF, regardless of its thickness, may not be related to brain damage in low risk term pregnancies.
dc.identifier.doi10.3109/14767058.2012.733754
dc.identifier.endpage236
dc.identifier.issn1476-7058
dc.identifier.issn1476-4954
dc.identifier.issue3
dc.identifier.pmid23030834
dc.identifier.scopus2-s2.0-84872329646
dc.identifier.scopusqualityQ1
dc.identifier.startpage233
dc.identifier.urihttps://doi.org/10.3109/14767058.2012.733754
dc.identifier.urihttps://hdl.handle.net/20.500.12428/23736
dc.identifier.volume26
dc.identifier.wosWOS:000313681200004
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofJournal of Maternal-Fetal & Neonatal Medicine
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectBrain damage
dc.subjectcord blood
dc.subjectmeconium-stained amniotic fluid
dc.subjectterm pregnancy
dc.subjectS100B
dc.titleCord blood S100B levels in low-risk term pregnancies with meconium-stained amniotic fluid
dc.typeArticle

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