Do 100-and 500-?T ELF magnetic fields alter beta-amyloid protein, protein carbonyl and malondialdehyde in rat brains?

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dc.authoridDasdag, Suleyman/0000-0003-1211-9677
dc.contributor.authorAkdag, Mehmet Zulkuf
dc.contributor.authorDasdag, Suleyman
dc.contributor.authorCakir, Dilek Ulker
dc.contributor.authorYokus, Beran
dc.contributor.authorKizil, Goksel
dc.contributor.authorKizil, Murat
dc.date.accessioned2025-01-27T20:31:34Z
dc.date.available2025-01-27T20:31:34Z
dc.date.issued2013
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractSeveral studies still state that presently accepted safety standards for extremely low-frequency magnetic fields (ELF-MFs) do not provide adequate protection, and therefore the standards are still open to question. To help resolve this question, the aim of this study was to illuminate the interaction between biomolecules and ELF-MFs by investigating the effect of ELF-MFs on beta-amyloid protein (BAP), protein carbonyl (PC) and malondialdehyde (MDA) in rat brain. For this study, 30 adult male Sprague-Dawley rats were used, which were divided into two experimental groups and a sham exposed group. Rats in two experimental groups were exposed to 100- and 500-mu T ELF-MFs (50 Hz) for 2 h/day for 10 months, which are the generally accepted safety standards for public and occupational exposures. The same procedures were applied to the rats in the sham group, but with the generator turned off. The results of this study showed that neither ELF-MFs used in this study altered BAP level significantly (p > 0.05). However, PC and MDA levels were increased by the exposure to 100- and 500-mu T ELF-MFs (p < 0.0001). In conclusion, both PC and MDA levels were altered by long-term exposure to either 100 or 500 mu T ELF-MF. However, many further and more comprehensive studies will be required to elucidate the interaction mechanisms between ELF-MFs exposure and living organisms.
dc.identifier.doi10.3109/15368378.2012.721848
dc.identifier.endpage372
dc.identifier.issn1536-8378
dc.identifier.issn1536-8386
dc.identifier.issue3
dc.identifier.pmid23324065
dc.identifier.scopus2-s2.0-84883145649
dc.identifier.scopusqualityQ2
dc.identifier.startpage363
dc.identifier.urihttps://doi.org/10.3109/15368378.2012.721848
dc.identifier.urihttps://hdl.handle.net/20.500.12428/23199
dc.identifier.volume32
dc.identifier.wosWOS:000323611200009
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Inc
dc.relation.ispartofElectromagnetic Biology and Medicine
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subject100-and 500-mu T extremely low-frequency magnetic fields
dc.subjectprotein carbonyl
dc.subjectmalondialdehyde
dc.subjectbeta-amyloid protein
dc.titleDo 100-and 500-?T ELF magnetic fields alter beta-amyloid protein, protein carbonyl and malondialdehyde in rat brains?
dc.typeArticle

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