Eosinophil count is related with coronary thrombus in non ST-elevated acute coronary syndrome

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dc.authoridTENEKECIOGLU, ERHAN/0000-0003-4376-2833
dc.contributor.authorTenekecioglu, Erhan
dc.contributor.authorYilmaz, Mustafa
dc.contributor.authorBekler, Adem
dc.contributor.authorDemir, Serafettin
dc.date.accessioned2025-01-27T20:11:54Z
dc.date.available2025-01-27T20:11:54Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBackground. White blood cells are reported as important not only in plaque vulnerability but also in thrombus formation and thrombus growth in acute coronary syndromes. Eosinophils contain granules that promote thrombus formation and thrombus growth in some heart diseases. In this study we aimed to investigate the relation of eosinophil count with coronary thrombus formation in patients with non ST-elevated acute coronary syndrome (NST-ACS). Method. A total of 251 consecutive patients were hospitalized in our hospital with a diagnosis of NST-ACS. Venous blood is collected for measurement of hematologic indices in all patients undergoing the coronary angiography. Coronary angiographies were performed in our clinic using the standard Judkins technique and angiographic assessment of the presence of thrombus was made. Results. During coronary angiography, coronary thrombus was not detected in 82 patients (Group 1). In the coronary angiography of 169 patients, coronary thrombus was detected at various grades (Group 2). While the neutrophil count (6.84 +/- 1.94 vs. 5.53 +/- 1.37; P<0.001) and eosinophil count (0.257 +/- 0.125 vs. 0.163 +/- 0.114; P<0.005) was significnatly increased in the group with coronary thrombus, the lymphocyte count (1.87 +/- 0.66 vs. 2.00 +/- 0.70; P<0.001) was significantly decreased in the group with coronary thrombus as compared to the patient group without coronary thrombus. In the correlation analyzes; presence of coronary thrombus is correlated with total cholesterol, LDL-C, total CK, CK-MB, troponin, total number of diseased coronary, platelet count, neutrophil count, lymphocyte count and eosinophil count. On multivariate linear regression analysis, total leukocyte count, neutrophil count, lymphocyte count, eosinophil count, troponin and total cholesterol was found to be independent predictor of coronary thrombus in patients with NST-ACS. Conclusion. Beside the increased neutrophil count, increased eosinophil count in CBC should alert the clinician about coronary thrombus development in patients with NST-ACS in order to make early medical interventions at acute phase of the disease.
dc.identifier.doi10.5507/bp.2014.039
dc.identifier.endpage271
dc.identifier.issn1213-8118
dc.identifier.issn1804-7521
dc.identifier.issue2
dc.identifier.pmid25030606
dc.identifier.scopus2-s2.0-84934325599
dc.identifier.scopusqualityQ2
dc.identifier.startpage266
dc.identifier.urihttps://doi.org/10.5507/bp.2014.039
dc.identifier.urihttps://hdl.handle.net/20.500.12428/20774
dc.identifier.volume159
dc.identifier.wosWOS:000359128900016
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherPalacky Univ, Medical Fac
dc.relation.ispartofBiomedical Papers-Olomouc
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectwhite blood cell
dc.subjecteosinophil
dc.subjectcoronary thrombus
dc.subjectcoronary artery disease
dc.subjectnon ST-elevated acute coronary syndromes
dc.titleEosinophil count is related with coronary thrombus in non ST-elevated acute coronary syndrome
dc.typeArticle

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