Genotyping of mumps virus circulating in Turkey in the 2006-2007 winter season

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dc.authoridAlper Akçalı/0000-0003-0325-886X
dc.authoridBUZGAN, TURAN/0000-0001-7897-3660
dc.contributor.authorAlper Akçalı
dc.contributor.authorYilmaz, Neziha
dc.contributor.authorUyar, Yavuz
dc.contributor.authorErtek, Mustafa
dc.contributor.authorBuzgan, Turan
dc.date.accessioned2025-01-27T20:57:56Z
dc.date.available2025-01-27T20:57:56Z
dc.date.issued2009
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractIn the winter of 2006-2007, several parotitis cases were reported in different provinces of Turkey. Serological and virological studies were undertaken to investigate these cases with the aim of determining the genotype of the mumps virus (MuV) circulating in Turkey. Samples from 23 cases-Ankara (n:5), Kirklareli (n:4), Mugla (n:10), Isparta (n:3), Trabzon (n:1)-with a diagnosis of clinical parotitis were investigated. Serum samples were tested against mumps IgM and IgG, nested PCR amplification of a 639-bp fragment encompassing the entire SH gene was performed using buccal swabs, and PCR products were sequenced. Of 18 serum samples, 16 (88.9%) were positive for mumps IgM. Seven (30.4%) of 23 buccal swab samples were positive by PCR. In five PCR-positive cases, the sample was also positive for mumps IgM, and serum samples were not available from two of the PCR- positive cases. There was 98% identity between the different sequences, and all were identified as genotype H. The sequences were most similar to sequences identified in Spain, Japan, Switzerland and the UK, and less closely related to the H strains identified in Belarus, Korea and Russia. This is the first report of the mumps virus genotypes circulating in Turkey. Turkey is, geographically, a bridge between Europe and Asia, and therefore, a better understanding of the molecular epidemiology of MuV in Turkey may led to improved tracking of the circulation of strains between the two continents. Moreover, there is a need to further investigate the existence of other genotypes in Turkey.
dc.identifier.doi10.1007/s00705-009-0519-1
dc.identifier.endpage1812
dc.identifier.issn0304-8608
dc.identifier.issn1432-8798
dc.identifier.issue11
dc.identifier.pmid19830379
dc.identifier.scopus2-s2.0-70350633408
dc.identifier.scopusqualityQ3
dc.identifier.startpage1807
dc.identifier.urihttps://doi.org/10.1007/s00705-009-0519-1
dc.identifier.urihttps://hdl.handle.net/20.500.12428/26558
dc.identifier.volume154
dc.identifier.wosWOS:000271198100010
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer Wien
dc.relation.ispartofArchives of Virology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectSh Protein
dc.subjectGene
dc.subjectIdentification
dc.subjectSequence
dc.subjectStrains
dc.titleGenotyping of mumps virus circulating in Turkey in the 2006-2007 winter season
dc.typeArticle

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