Accompanying Infections in Hospitalized Children with Neurological Disease

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dc.authoridKasap, Tolga/0000-0002-1046-7638
dc.authoridCokyaman, Turgay/0000-0002-7108-6839
dc.contributor.authorCokyaman, Turgay
dc.contributor.authorKasap, Tolga
dc.contributor.authorCelik, Taylan
dc.date.accessioned2025-01-27T20:52:02Z
dc.date.available2025-01-27T20:52:02Z
dc.date.issued2022
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractIntroduction: Infections in children with neurological disease often require hospitalization and are treated with antibiotics. In this study, it was aimed to determine the accompanying infections, antibiotics used and pathogenic microorganisms grown in cultures in hospitalized children with neurological disease. Materials and Methods: Digital medical files of patients between one month and 18 years old admitted to the pediatric neurology service were retrospectively analyzed. Diagnoses of neurological and infectious disease, antibiotics and antiepileptics used, and culture antibiogram results were recorded. Results: The most common infectious disease in children with neurological disease was lower respiratory tract infections (50%). Antibiotic use rate in children with neurological diseases was 51.9% (32.4% single and 19.4% combined). Lower respiratory tract infections (50%) were the leading antibiotic indications. Third generation cephalosporins (46%) were the most used in mono antibiotherapy, carbapenems (26.6%), gylicopeptides (26.6%) and broad-spectrum penicillins (10%) were used at higher rates in combined antibiotherapy. Pathogenic microorganisms such as Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Klebsiella pneumoniae, Morganella morganii and Enterococcus raffinosus were grown in urine cultures, Staphylococcus aureus and Enterococcus faecium in blood cultures. 59.3% of the children with neurological diseases were receiving antiepileptic treatment. Valproic acid 24.6%, levetiracetam 20.0%, phenobarbital and carbamazepine were used at 10.8% frequency. Conclusion: The most common infectious disease in hospitalized children with neurological disease is lower respiratory tract infections. Although cephalosporin is mostly preferred in mono-antibiotherapy, carbapenem and glycopeptides come to the fore in combined therapy. It is important to know the infections that may develop in the follow-up of this group of patients and the possible causative pathogens for rapid and effective treatment and to reduce health costs.
dc.identifier.doi10.4274/jcp.2022.81084
dc.identifier.endpage26
dc.identifier.issn1304-9054
dc.identifier.issn1308-6308
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85131175822
dc.identifier.scopusqualityQ4
dc.identifier.startpage17
dc.identifier.urihttps://doi.org/10.4274/jcp.2022.81084
dc.identifier.urihttps://hdl.handle.net/20.500.12428/25634
dc.identifier.volume20
dc.identifier.wosWOS:000837165400003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherGalenos Publ House
dc.relation.ispartofGuncel Pediatri-Journal of Current Pediatrics
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectAntiepileptics
dc.subjectantibiotics
dc.subjectchildren
dc.subjectpediatric
dc.subjecttreatment
dc.titleAccompanying Infections in Hospitalized Children with Neurological Disease
dc.title.alternativeHastaneye Yatırılan Nörolojik Hastalığı Olan Çocuklarda Eşlik Eden Enfeksiyonlar
dc.typeArticle

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