Effects of zinc oxide nanoparticles on bioaccumulation and oxidative stress in different organs of tilapia (Oreochromis niloticus)

Basit Öğe Kaydı
dc.authoridGurkan, Mert/0000-0001-7861-3999
dc.contributor.authorKaya, Hasan
dc.contributor.authorAydin, Fatih
dc.contributor.authorGurkan, Mert
dc.contributor.authorYılmaz, Sevdan
dc.contributor.authorAtes, Mehmet
dc.contributor.authorDemir, Veysel
dc.contributor.authorArslan, Zikri
dc.date.accessioned2025-01-27T20:20:10Z
dc.date.available2025-01-27T20:20:10Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractNano-size zinc oxide particles (ZnO NPs) are used in diverse industrial and commercial fields. However, the information from existing studies is not sufficient in evaluating the potential toxic effects of ZnO NPs. In this study, tilapia fish (Oreochromis niloticus) were exposed to different concentrations of small and large ZnO NPs in vivo. Accumulation in various organs/tissues (liver, gill, intestine, kidney, brain and muscle) and possible oxidative stress mechanisms were investigated comparatively. Fish were exposed to 1 and 10 mg/L concentrations of small (10-30 nm) and large (100 nm) ZnO NPs semi-statically for 14 days. Both small and large ZnO NPs accumulated substantially in the tissues. Accumulation for the small ZnO NPs was significantly higher compared to larger NPs under same exposure regimes. Significant fluctuations were observed in antioxidant defense system biomarkers, including Superoxide dismutase (SOD), Catalase (CAT) and Glutathione (GSH) levels depending on particle size, exposure time and concentration. Lipid peroxidation measured with TBARS levels were higher in groups exposed to the suspensions of small ZnO NPs than that of large ZnO NPs and controls. These results imply that colloidal suspensions of small ZnO NPs induce elevated oxidative stress and toxic effects on tilapia compared to the larger NPs. (C) 2015 Elsevier B.V. All rights reserved.
dc.description.sponsorshipCanakkale Onsekiz Mart University Scientific Foundation [2014/205]
dc.description.sponsorshipThis study was supported by the Canakkale Onsekiz Mart University Scientific Foundation (Project 2014/205).
dc.identifier.doi10.1016/j.etap.2015.10.001
dc.identifier.endpage947
dc.identifier.issn1382-6689
dc.identifier.issn1872-7077
dc.identifier.issue3
dc.identifier.pmid26513690
dc.identifier.scopus2-s2.0-84945944343
dc.identifier.scopusqualityQ1
dc.identifier.startpage936
dc.identifier.urihttps://doi.org/10.1016/j.etap.2015.10.001
dc.identifier.urihttps://hdl.handle.net/20.500.12428/21600
dc.identifier.volume40
dc.identifier.wosWOS:000366782300034
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Science Bv
dc.relation.ispartofEnvironmental Toxicology and Pharmacology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectZnO nanoparticles
dc.subjectToxicity
dc.subjectOxidative stress
dc.subjectAccumulation
dc.subjectTilapia (Oreochromis niloticus)
dc.titleEffects of zinc oxide nanoparticles on bioaccumulation and oxidative stress in different organs of tilapia (Oreochromis niloticus)
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu