Relationship between betatrophin levels and metabolic parameters in patients with polycystic ovary syndrome

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dc.contributor.authorErbag, G.
dc.contributor.authorEroglu, M.
dc.contributor.authorTurkon, H.
dc.contributor.authorSen, H.
dc.contributor.authorBinnetoglu, E.
dc.contributor.authorAylanc, N.
dc.contributor.authorAsik, M.
dc.date.accessioned2025-01-27T20:12:26Z
dc.date.available2025-01-27T20:12:26Z
dc.date.issued2016
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractTo evaluate the status of serum betatrophin levels and potential relations between metabolic parameters and betatrophin levels in patients with polycystic ovary syndrome. We included patients newly diagnosed with PCOS in our study. Fifty-seven female patients (30 patients with PCOS and 27 healthy control subjects) were enrolled in this study. Serum betatrophin levels were measured using a betatrophin enzyme-linked immunosorbent assay kit. Insulin resistance was calculated using the homeostasis model of the assessment-insulin resistance index formula. The betatrophin level was 1538,85 ng/L in the patient group and 2440,46 ng/L in the control group, and the difference was statistically significant (p=0.003). A significantly negative correlation was found between betatrophin level and insulin, HOMA-IR, and BMI. Betatrophin levels in patients with PCOS are lower than those without PCOS and inversely related to insulin resistance.
dc.identifier.doi10.14715/cmb/2016.62.5.4
dc.identifier.endpage24
dc.identifier.issn0145-5680
dc.identifier.issn1165-158X
dc.identifier.issue5
dc.identifier.pmid27188865
dc.identifier.scopus2-s2.0-84994812880
dc.identifier.scopusqualityQ4
dc.identifier.startpage20
dc.identifier.urihttps://doi.org/10.14715/cmb/2016.62.5.4
dc.identifier.urihttps://hdl.handle.net/20.500.12428/20944
dc.identifier.volume62
dc.identifier.wosWOS:000376592500005
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherC M B Assoc
dc.relation.ispartofCellular and Molecular Biology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectBetatrophin
dc.subjectinsulin resistance
dc.subjectpolycystic ovary syndrome
dc.titleRelationship between betatrophin levels and metabolic parameters in patients with polycystic ovary syndrome
dc.typeArticle

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