Myelin basic protein and ischemia modified albumin levels in acute ischemic stroke cases

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dc.authoridAKDUR, OKHAN/0000-0003-3099-6876
dc.contributor.authorCan, Serdar
dc.contributor.authorAkdur, Okhan
dc.contributor.authorYildirim, Ahmet
dc.contributor.authorAdam, Gurhan
dc.contributor.authorCakir, Dilek Ulker
dc.contributor.authorKaraman, Handan Isin Ozisik
dc.date.accessioned2025-01-27T20:20:21Z
dc.date.available2025-01-27T20:20:21Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: To investigate early diagnostic effects of serum myelin basic protein (MBP) and ischemic modified albumin (IMA) levels in patients with ischemic stroke. Methods: Fifty patients who presented to an emergency service with acute ischemic stroke between June 2013 to March 2014 were evaluated with the National Institute of Health Stroke Scale (NIHSS) and diffusion-weighted magnetic resonance imaging (MRI). Thirty four healthy cases were included as control group. All patients' serum IMA and MBP level were assessed. Results: Mean IMA value was 0.52 +/- 0.25 cases with acute ischemic stroke and serum IMA levels were significantly higher than the control group (p<0.01). No statistical significance was observed between acute ischemic stroke group and control group related to the MBP serum levels (P>0.05). Statistically significant correlation was detected between the volumes of diffusion restriction on MRI and NIHSS score (P=0.002,r=0.43) and IMA (P=0.015,r=0.344) levels. Conclusions: We have found that serum IMA levels are elevated in acute ischemic stroke cases and these levels are correlated with the ischemic tissue volume. MBP levels do not increase in early period of stroke cases.
dc.description.sponsorshipScientific Investigation Projects Directorate of Canakkale Onsekiz Mart University, Canakkale, Turkey
dc.description.sponsorshipScientific Investigation Projects Directorate of Canakkale Onsekiz Mart University, Canakkale, Turkey.
dc.identifier.doi10.12669/pjms.315.7702
dc.identifier.endpage1114
dc.identifier.issn1682-024X
dc.identifier.issue5
dc.identifier.pmid26648996
dc.identifier.scopus2-s2.0-84942043306
dc.identifier.scopusqualityQ1
dc.identifier.startpage1110
dc.identifier.urihttps://doi.org/10.12669/pjms.315.7702
dc.identifier.urihttps://hdl.handle.net/20.500.12428/21678
dc.identifier.volume31
dc.identifier.wosWOS:000365455900018
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherProfessional Medical Publications
dc.relation.ispartofPakistan Journal of Medical Sciences
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectAcute stroke
dc.subjectCerebral Ischemia
dc.subjectIschemia-modified serum albumin
dc.titleMyelin basic protein and ischemia modified albumin levels in acute ischemic stroke cases
dc.typeArticle

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