The Effects of Tubal Sterilization on the Tuba, Ovaries, and Endometrium in a Rat Model

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dc.contributor.authorDeniz, Rulin
dc.contributor.authorBaykuş, Yakup
dc.contributor.authorAdalı, Yasemen
dc.contributor.authorUzuner, Muhammet Bora
dc.contributor.authorÖztürk, Ömür
dc.date.accessioned2025-01-27T19:38:34Z
dc.date.available2025-01-27T19:38:34Z
dc.date.issued2019
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractAim: Although the etiology and physiopathology are not yet\rknown, the possible effects of tubal sterilization (TS) on ovarian\rfunction are still debated. Limited studies analyzed the histopathology\rof endometrium and ovaries after TS. In this study, we\raimed to evaluate the histopathological and biochemical changes\rof tubal sterilizations with the Pomeroy technique on tubal, ovarian,\rand endometrial tissues in rats.\rMaterial and Method: Twenty female Wistar albino rats were randomly\rdivided into two groups, with laparotomy only (Group 1)\rand laparotomy + TS (Group 2). Histopathological evaluation was\rperformed after Hematoxylin-Eosin staining. Follicle-stimulating\rhormone (FSH), estradiol (E2), and lactate dehydrogenase (LDH)\rlevels were biochemically measured.\rResults: In Group 2, there was inflammation, hyalinization and\rcongestion in the ovaries, tubas and endometrial tissues compared\rto Group 1. A statistically significant decrease in E2 (p <0.05) values\rwas detected in Group 2 compared to Group 1. In Group 2,\rmean FSH and LDH (p> 0.05) values were found to be increased,\ralthough not statistically significant, compared to Group 1.\rConclusion: We can say that tubal sterilization causes detrimental\reffects such as inflammatory cell infiltration in the ovaries of rats.\rFurther studies are needed to explain the possible mechanisms for\rthe reduced ovarian reserves after tubal sterilization.
dc.identifier.doi10.5505/kjms.2019.09471
dc.identifier.endpage190
dc.identifier.issn2146-2631
dc.identifier.issn2587-053X
dc.identifier.issue3
dc.identifier.startpage185
dc.identifier.trdizinid510504
dc.identifier.urihttps://doi.org/10.5505/kjms.2019.09471
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/510504
dc.identifier.urihttps://hdl.handle.net/20.500.12428/17267
dc.identifier.volume9
dc.indekslendigikaynakTR-Dizin
dc.language.isotr
dc.relation.ispartofKafkas Tıp Bilimleri Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TRD_20250125
dc.subjectBiyoloji
dc.subjectTıbbi Araştırmalar Deneysel
dc.subjectKadın Hastalıkları ve Doğum
dc.subjectGenel ve Dahili Tıp
dc.subjectBiyokimya ve Moleküler Biyoloji
dc.titleThe Effects of Tubal Sterilization on the Tuba, Ovaries, and Endometrium in a Rat Model
dc.typeArticle

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