A model for acute kidney injury in severe burn patients

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dc.authoridKARAKAYA, Emre/0000-0002-4879-7974
dc.authoridAYVAZOGLU SOY, EBRU/0000-0002-0993-9917
dc.authoridHaberal, Mehmet/0000-0002-3462-7632
dc.authoridYucebas, Sait Can/0000-0002-1030-3545
dc.authoridSayin, Burak/0000-0001-8287-6572
dc.authoridAkdur, Aydincan/0000-0002-8726-3369
dc.contributor.authorKarakaya, Emre
dc.contributor.authorAkdur, Aydincan
dc.contributor.authorAydogan, Cem
dc.contributor.authorTurk, Emin
dc.contributor.authorSayin, Cihat Burak
dc.contributor.authorSoy, Ebru Ayvazoglu
dc.contributor.authorYucebas, Sait Can
dc.date.accessioned2025-01-27T21:02:08Z
dc.date.available2025-01-27T21:02:08Z
dc.date.issued2022
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractIntroduction: In patients with severe burns, morbidity and mortality are high. One factor related to poor prognosis is acute kidney injury. According to the AKIN criteria, acute kidney injury has 3 stages based on urine output, serum creatinine level, and renal replacement therapy. In this study, we aimed to create a decision tree for estimating risk of acute kidney injury in patients with severe burn injuries. Methods: We retrospectively evaluated 437 adult patients with >20% total burn surface area injury who were treated at the Baskent University Ankara and Konya Burn Centers from January 2000 to March 2020. Patients who had high-voltage burn and previous history of kidney disease were excluded. Patient demographics, medical history, mechanism of injury, presence of inhalation injury, depth of burn, laboratory values, presence of oliguria, need for renal replacement therapy, central venous pressure, and prognosis were evaluated. These data were used in a decision tree method to create the Baskent University model to estimate risk of acute kidney injury in severe burn patients. Results: Our model provided an accuracy of 71.09% for risk estimation. Of 172 patients, 78 (45%) had different degrees of acute kidney injury, with 26 of these (15.1%) receiving renal replacement therapy. Our model showed that total burn surface area was the most important factor for estimation of acute kidney injury occurrence. Other important factors included serum creatinine value, burn injury severity score, hemoglobin value, neutrophil-tolymphocyte ratio, and platelet count. Conclusion: The Baskent University model for acute kidney injury may be helpful to determine risk of acute kidney injury in burn patients. This determination would allow appropriate treatment to be given to high-risk patients in the early period, reducing the incidence of acute kidney injury. (c) 2021 Published by Elsevier Ltd.
dc.identifier.doi10.1016/j.burns.2021.04.004
dc.identifier.endpage77
dc.identifier.issn0305-4179
dc.identifier.issn1879-1409
dc.identifier.issue1
dc.identifier.pmid33879373
dc.identifier.scopus2-s2.0-85104356060
dc.identifier.scopusqualityQ1
dc.identifier.startpage69
dc.identifier.urihttps://doi.org/10.1016/j.burns.2021.04.004
dc.identifier.urihttps://hdl.handle.net/20.500.12428/27290
dc.identifier.volume48
dc.identifier.wosWOS:000744127400008
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Sci Ltd
dc.relation.ispartofBurns
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectBurns
dc.subjectAcute kidney injury
dc.subjectResuscitation
dc.titleA model for acute kidney injury in severe burn patients
dc.typeArticle

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