A PEDICLED MUSCLE FLAP BASED SOLELY ON A NEURAL PEDICLE

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dc.authoridKuzon, William/0000-0001-8752-703X
dc.contributor.authorAvci, Gulden
dc.contributor.authorAkan, Mithat
dc.contributor.authorAkoz, Tayfun
dc.contributor.authorKuzon, William
dc.contributor.authorGul, Aylin Ege
dc.date.accessioned2025-01-27T20:24:34Z
dc.date.available2025-01-27T20:24:34Z
dc.date.issued2009
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractWe tested the hypothesis that the intrinsic vascular plexus of the motor nerve could support viability in a rat hindlimb muscle flap. In a preliminary study, we examined the course and vascularity of the sciatic nerve, the peroneal nerve, and the peroneous longus muscle in the rat hindlimb via anatomic dissection, microangiography, and histologic study (n = 10 animals). On the basis of this examination, the peroneous longus muscle was chosen as our experimental model in this study. In 12 animals, the peroneus longus was acutely elevated, which severed all tendinous and vascular structures, this left the muscle pedicled on the motor nerve only (Group 1). Animals in Group 11 underwent a staged elevation of the flap with division of the vascular pedicle, the tendon of insertion, and the tendon of origin during separate procedures that were 5 days apart (n = 12). Muscle viability was evaluated by gross inspection, measurement of muscle weight and length, nitroblue tetrazlium (NBT) staining, microangiography, and histology. NBT staining demonstrated that immediate elevation of the peroneus longus muscle flaps led to an average necrotic area of 80.6% +/- 9.8% (Group 1). A significant improvement in viability was observed for muscle flaps of animals in Group II, with peroneus longus muscle necrosis averaging 25.6% +/- 9.3%. Microangiography demonstrated that the intrinsic vascularity of nerve was increased dramatically in Group II. These data support the hypothesis that the intrinsic vascular plexus of the motor nerve of a skeletal muscle can support at least partial viability of a muscle flap. However, this vascular axis is inadequate to support complete viability of a muscle flap if the flap is elevated immediately. If a staged elevation affects a surgical delay, the viability of a muscle flap elevated on a neural pedicle can be increased significantly. With adjustments in the delay procedure, this strategy may allow transfer of muscle flaps when maintenance or reconstitution of the primary vascular axis is not possible. (C) 2009 Wiley-Liss, Inc. Microsurgery 29:218-225, 2009.
dc.identifier.doi10.1002/micr.20609
dc.identifier.endpage225
dc.identifier.issn0738-1085
dc.identifier.issue3
dc.identifier.pmid19205060
dc.identifier.scopus2-s2.0-63049091708
dc.identifier.scopusqualityQ2
dc.identifier.startpage218
dc.identifier.urihttps://doi.org/10.1002/micr.20609
dc.identifier.urihttps://hdl.handle.net/20.500.12428/22280
dc.identifier.volume29
dc.identifier.wosWOS:000264417700009
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley-Liss
dc.relation.ispartofMicrosurgery
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectDelay Phenomenon
dc.subjectSciatic-Nerve
dc.subjectBlood-Flow
dc.subjectMusculocutaneous Flap
dc.subjectVascular Delay
dc.subjectSurgical Delay
dc.subjectSkin Flaps
dc.subjectModel
dc.subjectRat
dc.subjectViability
dc.titleA PEDICLED MUSCLE FLAP BASED SOLELY ON A NEURAL PEDICLE
dc.typeArticle

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