Electrocatalytic Oxidation of Acyclovir on Poly(p-Aminobenzene Sulfonic Acid) Film Modified Glassy Carbon Electrode
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Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley-V C H Verlag Gmbh
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Acyclovir is an antiviral effective drug active compound. A glassy carbon electrode (GCE) was modified with an electropolymerized film of p-aminobenzene sulfonic acid (p-ABSA) in phosphate buffer solution (PBS). The polymer film-modified electrode was used to electrochemically detect acyclovir. Polymer film showed excellent electrocatalytic activity for the oxidation of acyclovir. The anodic peak potential value of the acyclovir at the poly(p-ABSA) modified glassy carbon electrode was 950mV obtained by DPV. A linear calibration curve for DPV analysis was constructed in the acyclovir concentration range 2x10(-7)-9x10(-6)molL(-1). Limit of detection (LOD) and limit of quantification (LOQ) were obtained as 5.57x10(-8) and 1.85x10(-7)molL(-1) respectively. The proposed method exhibits good recovery and reproducibility.
Açıklama
Anahtar Kelimeler
p-Aminobenzene sulfonic acid, Modified-glassy carbon electrode, Electropolymerization, Electrocatalytic oxidation, Determination of acyclovir, Voltammetry
Kaynak
Electroanalysis
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
27
Sayı
10
