One pot, multicomponent protocol for the synthesis of novel imidazo[1,2-a]pyrimidine-based pyran analogs: a potential biological scaffold

dc.authoridGungor, Tugba/0000-0001-5261-1856
dc.contributor.authorGungor, Tugba
dc.date.accessioned2025-01-27T20:57:44Z
dc.date.available2025-01-27T20:57:44Z
dc.date.issued2020
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractAn efficient procedure between imidazo[1,2-a]pyrimidine-2-carbaldehyde, malononitrile, enolizable C-H activated acidic compounds, and sodium carbonate is described for the synthesis of potential biologically active, novel imidazo[1,2-a]pyrimidine-based pyran analogs through one pot, multicomponent reactions at room temperature. This method provided mild reaction conditions, simple purification without column chromatography, and moderate to good yields for the construction of imidazo[1,2-a]pyrimidine-based pyran derivatives. The structures of target compounds were established with different spectroscopic analyses. [GRAPHICS] .
dc.identifier.doi10.1007/s00706-020-02601-w
dc.identifier.endpage789
dc.identifier.issn0026-9247
dc.identifier.issn1434-4475
dc.identifier.issue5
dc.identifier.scopus2-s2.0-85084458524
dc.identifier.scopusqualityQ2
dc.identifier.startpage781
dc.identifier.urihttps://doi.org/10.1007/s00706-020-02601-w
dc.identifier.urihttps://hdl.handle.net/20.500.12428/26466
dc.identifier.volume151
dc.identifier.wosWOS:000531917700002
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherSpringer Wien
dc.relation.ispartofMonatshefte Fur Chemie
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectChromenes
dc.subjectImidazo[1
dc.subject2-a]pyrimidines
dc.subjectPyrans
dc.subjectMulticomponent reactions (MCRs)
dc.subjectOne-pot synthesis
dc.titleOne pot, multicomponent protocol for the synthesis of novel imidazo[1,2-a]pyrimidine-based pyran analogs: a potential biological scaffold
dc.typeArticle

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