Acute exposure to boron in Nile tilapia (Oreochromis niloticus): Median-lethal concentration (LC50), blood parameters, DNA fragmentation of blood and sperm cells

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dc.authoridInanan, Burak/0000-0002-2888-8457
dc.authoridKESBIC, Osman Sabri/0000-0002-1576-1836
dc.contributor.authorAcar, Umit
dc.contributor.authorInanan, Burak Evren
dc.contributor.authorZemheri, Fahriye
dc.contributor.authorKesbic, Osman Sabri
dc.contributor.authorYilmaz, Sevdan
dc.date.accessioned2025-01-27T20:35:06Z
dc.date.available2025-01-27T20:35:06Z
dc.date.issued2018
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractRecently, Boron (B) contamination of aquatic ecosystem has received considerable critical attention due to its toxic effects at high concentrations on plants as well as animals. Previous studies on toxic effects of B have not dealt with DNA damages in blood and sperm cells of Nile tilapia (Oreochromis niloticus), together with blood parameters. This study consisted of two successive experiments purposes to determine these findings, including the median-lethal concentration (LC50) of B for Nile tilapia. In the first one, at 96 h, LC50 of B for Nile tilapia was 141.42 mg L-1 B. In the second one, Nile tilapia were treated with five elevated B concentrations (1, 5, 25, 50 and 100 mg L-1 B) and hematological, serum biochemical parameters, and DNA damages of Nile tilapia in these treatments were determined comparing with the control after 14 days of exposure. Hematological parameters (red blood cell count, hematocrit, and hemoglobin) were similar to each other in all groups while serum biochemical parameters (glucose, total protein, cholesterol, alkaline phosphatase, glutamic oxaloacetic transaminase, and glutamic pyruvic transaminase) in B treatments, especially in 50 and 100 mg L-1 B groups, were found significantly higher (P < 0.05). DNA fragmentation was detected in all blood cells in >= 25 mg L-1 B treatments, while all sperm cells in 100 mg L-1 B treatments. These results demonstrated the harmful effects of B at high concentration (50 and 100 mg L-1 B) on the DNA integrity of blood and sperm cells, and also the serum biochemical parameters. (C) 2018 Elsevier Ltd. All rights reserved.
dc.identifier.doi10.1016/j.chemosphere.2018.09.063
dc.identifier.endpage350
dc.identifier.issn0045-6535
dc.identifier.issn1879-1298
dc.identifier.pmid30241078
dc.identifier.scopus2-s2.0-85054816739
dc.identifier.scopusqualityQ1
dc.identifier.startpage345
dc.identifier.urihttps://doi.org/10.1016/j.chemosphere.2018.09.063
dc.identifier.urihttps://hdl.handle.net/20.500.12428/23569
dc.identifier.volume213
dc.identifier.wosWOS:000448493700037
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherPergamon-Elsevier Science Ltd
dc.relation.ispartofChemosphere
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectOreochromis niloticus
dc.subjectBoron
dc.subjectComet assay
dc.subjectBlood
dc.subjectSperm
dc.titleAcute exposure to boron in Nile tilapia (Oreochromis niloticus): Median-lethal concentration (LC50), blood parameters, DNA fragmentation of blood and sperm cells
dc.typeArticle

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