Association between mean platelet volume and disease severity in patients with psoriasis and psoriatic arthritis

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dc.authoridHIZ, Meliha Merve/0000-0003-4303-9717
dc.contributor.authorKilic, Sevilay
dc.contributor.authorResorlu, Hatice
dc.contributor.authorIsik, Selda
dc.contributor.authorOymak, Sibel
dc.contributor.authorAkbal, Ayla
dc.contributor.authorHiz, Meliha Merve
dc.contributor.authorOgretmen, Zerrin
dc.date.accessioned2025-01-27T20:55:50Z
dc.date.available2025-01-27T20:55:50Z
dc.date.issued2017
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractIntroduction: Mean platelet volume (MPV) is an important marker that shows the activation and function of the platelets, which is effective in the inflammatory diseases. Aim: To show the relationship between MPV and the development of psoriatic arthritis (PA) in patients with psoriasis vulgaris (PV) and the correlation between MPV and psoriasis severity score (PASI). Material and methods: Our study included 116 patients with psoriatic arthritis (68 female, 48 male) and 41 patients in the psoriasis group (19 female, 22 male) and 90 subjects in the control group (55 female, 35 male). The demographic data of the patients, duration of disease, PAS', the nature of the disease were evaluated retrospectively. Results: Mean platelet volume levels of both the PV group (8.79 +/- 0.86 fl) and the PA group (9.18 +/- 1.26 fl) were significantly higher compared to the control group (8.42 +/- 0.74 fl). There was a weak statistically positive correlation between the PASI and the MPV according to the correlation analysis (r = 0.165; p = 0.046). Conclusions: Our results show that MPV may be helpful as an indicator of the clinical course of PV and PA. In this regard, that study should be supported by prospective studies to find strong correlations.
dc.identifier.doi10.5114/ada.2017.67076
dc.identifier.endpage130
dc.identifier.issn1642-395X
dc.identifier.issue2
dc.identifier.pmid28507491
dc.identifier.scopus2-s2.0-85018162172
dc.identifier.scopusqualityQ2
dc.identifier.startpage126
dc.identifier.urihttps://doi.org/10.5114/ada.2017.67076
dc.identifier.urihttps://hdl.handle.net/20.500.12428/26203
dc.identifier.volume34
dc.identifier.wosWOS:000400804400007
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTermedia Publishing House Ltd
dc.relation.ispartofPostepy Dermatologii I Alergologii
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectmean platelet volume
dc.subjectpsoriasis
dc.subjectpsoriatic arthritis
dc.subjectmean platelet volume
dc.subjectpsoriasis severity score
dc.titleAssociation between mean platelet volume and disease severity in patients with psoriasis and psoriatic arthritis
dc.typeArticle

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