Water Dynamics in Dextran-Based Hydrogel Micro/Nanoparticles Studied by NMR Diffusometry and Relaxometry

Basit Öğe Kaydı
dc.authoridŞahiner, Nurettin / 0000-0003-0120-530X
dc.contributor.authorUmut, Evrim
dc.contributor.authorBeira, Maria Jardim
dc.contributor.authorÖztop, Mecit Halil
dc.contributor.authorŞahiner, Nurettin
dc.contributor.authorSebastiao, Pedro Jose
dc.contributor.authorKruk, Danuta
dc.date.accessioned2025-01-27T20:31:16Z
dc.date.available2025-01-27T20:31:16Z
dc.date.issued2023
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractWater dynamics in mesoporous dextran hydrogel micro/nanoparticles was investigated by means of nuclear magnetic resonance (NMR) techniques. High-resolution H-1 NMR spectra and pulsed field gradient (PFG) NMR diffusometry measurements obtained on swollen state dextran micro/nanogel revealed the existence of different fractions of water molecules based on their interaction with the gel matrix. In addition to the translational diffusion of bulk water, two more diffusion processes characterized with self-diffusion coefficients 1 and 2 orders of magnitude smaller than that of bulk water were identified. H-1 spin-lattice relaxation dispersion profiles obtained for a broad range of Larmor frequencies using fast field cycling (FFC) and conventional NMR relaxometry techniques allowed us to further clarify the mechanisms of molecular motion. According to the water proton pool fractions and associated self-diffusion coefficients, it is shown that the relaxation contribution associated with reorientation-mediated translational motions (RMTDs) dominates the relaxation dispersion observed at intermediate frequencies. At very low frequencies, the spin-lattice relaxation rate is dominated by the slow solid-gel dynamics probed by the water molecules interacting with the pores' surface hydroxyl groups due to the rapid chemical exchange between surface hydroxyl groups and free water. The correlation time for the thumbling-like motion of the dextran gel was found to be in the submillisecond range. The values of the self-diffusion and coherence lengths associated with motion of water molecules interacting with the solid-gel particles are consistent with the particle size and pore size distributions obtained for the studied dextran gels.
dc.description.sponsorshipMiddle East Technical University, Scientific Research Coordination Office [ADEP-314-2022-11184]
dc.description.sponsorshipThis work received funding from MiddleEast TechnicalUniversity, Scientific Research Coordination Office, grant# ADEP-314-2022-11184.Anant Kumar is acknowledged for his help in relaxation time measurementsat high fields.
dc.identifier.doi10.1021/acs.jpcb.3c04452
dc.identifier.endpage8960
dc.identifier.issn1520-6106
dc.identifier.issn1520-5207
dc.identifier.issue41
dc.identifier.pmid37812396
dc.identifier.scopus2-s2.0-85174751822
dc.identifier.scopusqualityQ2
dc.identifier.startpage8950
dc.identifier.urihttps://doi.org/10.1021/acs.jpcb.3c04452
dc.identifier.urihttps://hdl.handle.net/20.500.12428/23062
dc.identifier.volume127
dc.identifier.wosWOS:001082713800001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAmer Chemical Soc
dc.relation.ispartofJournal of Physical Chemistry B
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectField-Cycling Nmr
dc.subjectTranslational Diffusion
dc.subjectMolecular-Dynamics
dc.subjectSolvent Dynamics
dc.subjectSelf-Diffusion
dc.subjectPorous-Media
dc.subjectRelaxation
dc.subjectLiquids
dc.subjectSurfaces
dc.subjectH-1-Nmr
dc.titleWater Dynamics in Dextran-Based Hydrogel Micro/Nanoparticles Studied by NMR Diffusometry and Relaxometry
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
Nurettin Sahiner_Makale.pdf
Boyut:
4.91 MB
Biçim:
Adobe Portable Document Format
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Kimya Bölümü Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu