Orlistat-induced molecular bio-imprinting of microbial lipase

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dc.authoridYılmaz, Emin/0000-0003-1527-5042
dc.contributor.authorYilmaz, E
dc.date.accessioned2025-01-27T20:39:12Z
dc.date.available2025-01-27T20:39:12Z
dc.date.issued2003
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractSome microbial lipases bio-imprinted with the reversible lipase inhibitor, Orlistat. Comparison of interesterification activities indicated that Orlistat bio-imprinting is equally effective as amphiphile imprinting and yields a 3.5-4.0-fold activity enhancement. Solvent-free incubation medium was as effective as hexane medium. Water addition into the incubation medium erased the bio-imprinting effect; hence, lid opening should be the mechanism of activation. This study provides additional proof to the hypothesis that lipase bio-imprinting is an active-site related phenomenon.
dc.identifier.doi10.1023/A:1023216301165
dc.identifier.endpage165
dc.identifier.issn0959-3993
dc.identifier.issue2
dc.identifier.scopus2-s2.0-0038069176
dc.identifier.scopusqualityQ2
dc.identifier.startpage161
dc.identifier.urihttps://doi.org/10.1023/A:1023216301165
dc.identifier.urihttps://hdl.handle.net/20.500.12428/23889
dc.identifier.volume19
dc.identifier.wosWOS:000182132100009
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherKluwer Academic Publ
dc.relation.ispartofWorld Journal of Microbiology & Biotechnology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectbio-imprinting
dc.subjectenhancement
dc.subjectinteresterification
dc.subjectlipase
dc.subjectOrlistat
dc.titleOrlistat-induced molecular bio-imprinting of microbial lipase
dc.typeArticle

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