Osmotic Demyelination Syndrome in A Normonatremic Patient with Chronic Kidney Disease

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dc.authoridOcak, Ozgul/0000-0001-8276-0174
dc.authoridKorkmazer, Bora/0000-0001-7015-365X
dc.contributor.authorOcak, Ozgul
dc.contributor.authorUrfali, Furkan Erturk
dc.contributor.authorKorkmazer, Bora
dc.contributor.authorKaraman, Handan Isin Ozisik
dc.date.accessioned2025-01-27T20:20:19Z
dc.date.available2025-01-27T20:20:19Z
dc.date.issued2020
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractOsmotic demyelination syndrome (ODS), also known as central pontine myelinolysis, is a neurological disorder characterised by myelin loss in the central pons and other parts of the brain, such as the basal ganglia, lateral geniculate bodies, external and internal capsules and cerebellum. ODS is a demyelinating disorder associated with rapid correction of hyponatraemia. Classically, this is associated with hyponatraemia, but it can also occur in the presence of normonatremia. Changes in osmolality are found to be responsible in the pathogenesis of the lesions. Rarely, pontine myelinosis with delirium was also described in normonatremic patients. We report the clinical and radiological findings of a normonatremic 45-year-old female patient with chronic kidney disease, who experienced central pontine myelinolysis. This report aims to show that pontine myelinolysis may also occur in normonatremic circumstances, and early, rapid management of the disorder is important to prevent permanent damage.
dc.identifier.doi10.4274/meandros.galenos.2017.94803
dc.identifier.endpage92
dc.identifier.issn2149-9063
dc.identifier.issue1
dc.identifier.startpage89
dc.identifier.trdizinid449264
dc.identifier.urihttps://doi.org/10.4274/meandros.galenos.2017.94803
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/449264
dc.identifier.urihttps://hdl.handle.net/20.500.12428/21665
dc.identifier.volume21
dc.identifier.wosWOS:000543352900014
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherGalenos Yayincilik
dc.relation.ispartofMeandros Medical and Dental Journal
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectOsmotic demyelination syndrome
dc.subjectnormonatremia
dc.subjectchronic kidney disease
dc.titleOsmotic Demyelination Syndrome in A Normonatremic Patient with Chronic Kidney Disease
dc.typeArticle

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