Three-Decade Analysis of Inflammatory Bowel Disease in Türkiye: A Multicenter Study (1993-2024)

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dc.authorid0000-0002-7037-5233
dc.authorid0000-0002-2538-857X
dc.authorid0000-0001-5477-9492
dc.authorid0000-0003-1561-8789
dc.contributor.authorDurak, Muhammed Bahaddin
dc.contributor.authorCagin, Yasir Furkan
dc.contributor.authorBalkan, Ayhan
dc.contributor.authorCoskun, Yusuf
dc.contributor.authorKarakan, Tarkan
dc.contributor.authorCagir, Yavuz
dc.contributor.authorBeyazit, Yavuz
dc.date.accessioned2026-02-03T11:59:42Z
dc.date.available2026-02-03T11:59:42Z
dc.date.issued2025
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBackground/Aims: Inflammatory bowel diseases (IBDs) are increasingly prevalent and challenging globally. Data regarding IBD fre quency and severity between Europe and Asia are needed. The aim was to investigate the trend of IBD in T & uuml;rkiye during the last 3 decades. Materials and Methods: The study was conducted retrospectively at 14 centers in T & uuml;rkiye between June 1993 and March 2024. Results: Over 30 years, 4308 patients, of whom 2507 (58.2%) had ulcerative colitis (UC) and 1717 (39.9%) had Crohn's Disease (CD), were included in the study. The overall median age at the onset of IBD was 34.43 (25.28-45.64) years; the age at onset of IBD was younger in CD compared to UC (32.72 vs. 35.52 years respectively, P < .001). The peak age onset range was 28-32 years in CD, whereas 23-27 years in UC. Overall, 2526 (58.6%) patients were male. The most common location was left-sided colitis in UC patients (45.1%), followed by extensive colitis (31.2%), and proctitis (23.7%), while ileal involvement in CD patients (45.2%), afterward ileocolonic (409%), and colonic (13.5%). Both illnesses are becoming increasingly prevalent. The UC/CD ratio tends to decrease over time. During the study period, 1577 (36.6%) patients received biologic treatment. During the study period, 418 (24.3%) underwent resective surgery for CD and 88 (3.5%) total colectomy for UC; the major abdominal surgery has declined over time. Conclusion: The frequency and characteristic features of IBD in T & uuml;rkiye appear to be between Europe and Asia. Over time, while the usage of biologic therapy and the rate of CD have increased, the frequency of surgery has decreased.
dc.identifier.doi10.5152/tjg.2025.25063
dc.identifier.issn2148-5607
dc.identifier.issue12
dc.identifier.pmid41340405
dc.identifier.scopus2-s2.0-105022911936
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.5152/tjg.2025.25063
dc.identifier.urihttps://hdl.handle.net/20.500.12428/34380
dc.identifier.volume36
dc.identifier.wosWOS:001634573300004
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAves
dc.relation.ispartofTurkish Journal of Gastroenterology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20260130
dc.subjectCrohn's disease
dc.subjectinflammatory bowel disease
dc.subjectulcerative colitis
dc.titleThree-Decade Analysis of Inflammatory Bowel Disease in Türkiye: A Multicenter Study (1993-2024)
dc.typeArticle

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