A novel id-iri score: development and internal validation of the multivariable community acquired sepsis clinical risk prediction model

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dc.authoridEl-Sokkary, Rehab/0000-0002-8135-7671
dc.authoridGrgic, Svjetlana/0000-0003-2543-9987
dc.authoridPuca, Edmond/0000-0002-0621-4865
dc.authoridErdem, Hakan/0000-0002-6265-5227
dc.authoridCag, Yasemin/0000-0002-9983-0308
dc.authoridatilla, aynur/0000-0001-8027-1991
dc.authoridUysal, Serhat/0000-0002-4294-5999
dc.contributor.authorDiktas, Husrev
dc.contributor.authorUysal, Serhat
dc.contributor.authorErdem, Hakan
dc.contributor.authorCag, Yasemin
dc.contributor.authorMiftode, Egidia
dc.contributor.authorDurmus, Gul
dc.contributor.authorUlu-Kilic, Aysegul
dc.date.accessioned2025-01-27T20:20:39Z
dc.date.available2025-01-27T20:20:39Z
dc.date.issued2020
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractWe aimed to develop a scoring system for predicting in-hospital mortality of community-acquired (CA) sepsis patients. This was a prospective, observational multicenter study performed to analyze CA sepsis among adult patients through ID-IRI (Infectious Diseases International Research Initiative) at 32 centers in 10 countries between December 1, 2015, and May 15, 2016. After baseline evaluation, we used univariate analysis at the second and logistic regression analysis at the third phase. In this prospective observational study, data of 373 cases with CA sepsis or septic shock were submitted from 32 referral centers in 10 countries. The median age was 68 (51-77) years, and 174 (46,6%) of the patients were females. The median hospitalization time of the patients was 15 (10-21) days. Overall mortality rate due to CA sepsis was 17.7% (n = 66). The possible predictors which have strong correlation and the variables that cause collinearity are acute oliguria, altered consciousness, persistent hypotension, fever, serum creatinine, age, and serum total protein. CAS (%) is a new scoring system and works in accordance with the parameters in third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). The system has yielded successful results in terms of predicting mortality in CA sepsis patients.
dc.identifier.doi10.1007/s10096-019-03781-y
dc.identifier.endpage701
dc.identifier.issn0934-9723
dc.identifier.issn1435-4373
dc.identifier.issue4
dc.identifier.pmid31823148
dc.identifier.scopus2-s2.0-85076589753
dc.identifier.scopusqualityQ1
dc.identifier.startpage689
dc.identifier.urihttps://doi.org/10.1007/s10096-019-03781-y
dc.identifier.urihttps://hdl.handle.net/20.500.12428/21774
dc.identifier.volume39
dc.identifier.wosWOS:000520706000011
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofEuropean Journal of Clinical Microbiology & Infectious Diseases
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectSepsis
dc.subjectmortality
dc.subjectCommunity acquired
dc.subjectScoring system
dc.subjectSepsis-3
dc.titleA novel id-iri score: development and internal validation of the multivariable community acquired sepsis clinical risk prediction model
dc.typeArticle

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