Relationship between Abdominal Aortic Intima Media Thickness and Central Obesity in Children

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dc.authoridAylanc, Hakan/0000-0002-8907-3809
dc.contributor.authorAylanc, Hakan
dc.contributor.authorAylanc, Nilufer
dc.contributor.authorYildirim, Sule
dc.contributor.authorTekin, Mustafa
dc.contributor.authorBattal, Fatih
dc.contributor.authorKaymaz, Nazan
dc.contributor.authorBinnetoglu, Fatih Koksal
dc.date.accessioned2025-01-27T20:20:09Z
dc.date.available2025-01-27T20:20:09Z
dc.date.issued2016
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBackground: Childhood obesity is one of the important risk factors for early atherosclerosis. We aimed to evaluate the effect of obesity on abdominal aortic intima media thickness (aaIMT) in children. Methods: We consecutively recruited 60 obese and 28 healthy children from the outpatient clinic of pediatrics. In all patients, BMI, waist circumference (WC) and hip circumference (HC) were measured, and fasting serum lipid profile, plasma glucose and plasma insulin were studied. Homeostasis model assessment-estimated insulin resistance (HOMA-IR) was calculated for the obese group. All children underwent ultrasonography to evaluate hepatosteatosis and to measure aaIMT. Results: There was a significant difference between the groups in terms of aaIMT, insulin, glucose, HOMA-IR, total cholesterol, low-density lipoprotein, triglyceride and hepatosteatosis. aaIMT was 1.12 +/- 0.25 and 0.61 +/- 0.18 mm in the obese and nonobese groups, respectively (p < 0.001). In the obese group, there was a positive correlation between aaIMT and WC, WC/height ratio, BMI, HC and hepatosteatosis (p < 0.05 for all), with the highest significance for WC. Conclusions: This study showed that aaIMT was significantly higher in obese children than in nonobese children, and that WC was a strong predictor for aaIMT. Early detection of an increased aaIMT in obese children may guide the follow-up of these patients in terms of developing atherosclerosis and its complications. (C) 2015 S. Karger AG, Basel
dc.identifier.doi10.1159/000442156
dc.identifier.endpage48
dc.identifier.issn1663-2818
dc.identifier.issn1663-2826
dc.identifier.issue1
dc.identifier.pmid26600251
dc.identifier.scopus2-s2.0-84956775400
dc.identifier.scopusqualityQ1
dc.identifier.startpage43
dc.identifier.urihttps://doi.org/10.1159/000442156
dc.identifier.urihttps://hdl.handle.net/20.500.12428/21584
dc.identifier.volume85
dc.identifier.wosWOS:000369332600008
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherKarger
dc.relation.ispartofHormone Research in Paediatrics
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectChildren
dc.subjectObesity
dc.subjectAbdominal aorta
dc.subjectWaist circumference
dc.subjectAtherosclerosis
dc.titleRelationship between Abdominal Aortic Intima Media Thickness and Central Obesity in Children
dc.typeArticle

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