Potent antibacterial activity of oligo-3-aminopyridine against Staphylococcus aureus and Enterococcus faecalis
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Tarih
2004
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Natl Inst Science Communication
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Oligo-3-aminopyridine (OAP) was tested for its antibacterial activity against two gram positive (Staphylococcus aureus and Enterococcus faecalis) and two gram negative (Escherchia coli and Pseudomonas aeruginosa) bacterial strains. Antibacterial efficacy was measured by disk diffusion assay. Inhibition zones demonstrated that 50 mug OAP showed strong antibacterial activity against the gram-positive strains; the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were found to be 25 mug/ml and 50 mug/ml, respectively. The results indicate that OAP is a potent antibacterial agent against S. aureus and E. faecalis.
Açıklama
Anahtar Kelimeler
antibacterial activity, S. aureus, E. faecalis, oligo-3-aminopyridine
Kaynak
Indian Journal of Biochemistry & Biophysics
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
41
Sayı
2-3
